Response:

We thank Drs Garman and McCall1 for their valuable comments and interest in our recent article in the January issue of Gastrointestinal Endoscopy.2 They bring up 2 separate issues: (1) the role of submucosal glands/ducts in the pathogenesis of Barrett's esophagus (BE) and BE-associated neoplasia and (2) the resemblance, in their opinion, of subsquamous glands in Figure 2A of our article to foci of acinar "ductal metaplasia" that they have previously reported in esophageal submucosal glands (ESMGs) in esophagectomies performed for BE-associated high-grade dysplasia (HGD) or adenocarcinoma.

https://ift.tt/2M6jejU