The Expanding Role of Physiologic Imaging in Radiation Oncology

Functional imaging of tumor and normal tissue physiology provides novel opportunities to further optimize radiation therapy (RT) treatments by identifying refined critical structures and biological target volumes (BTVs) within the tumor for preferential targeting. Advances in functional imaging and adaptive RT techniques have the potential to lead to the development of improved dose–response relationships for normal tissues and RT treatments that are tailored to individual patients. In this "Oncology Scan" for the special issue on Imaging in Radiation Oncology, members of the physics editorial team discuss 3 thought-provoking articles that reflect recent and noteworthy advances in the combined use of functional imaging and adaptive RT to exploit heterogeneity in tumor and normal tissue biology.

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