Patients with colorectal cancer have identical strains of Fusobacterium nucleatum in their colorectal cancer and oral cavity

We read with great interest the article by Flemer et al, which suggests that analysis of the oral microbiota could potentially be used as a screening method for colorectal cancer (CRC) and polyp detection.1 Fusobacterium (F.) nucleatum is one of the most densely colonised bacterial species in the oral cavity and is known to be associated with periodontitis.2 Recently, many researchers have demonstrated that F. nucleatum is related to CRC development and pathogenicity.3 4 However, the relationship between F. nucleatum in CRC and the oral cavity is not well understood. For this purpose, we examined whether identical strains of F. nucleatum could be isolated from CRC and saliva specimens obtained from the same patient. The approach used in this study is detailed in figure 1A (see online  for details). We collected CRC and saliva samples from 14 patients (online ) and isolated bacteria...

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