Expansile invasive growth pattern is definite evidence for the diagnosis of small hepatocellular carcinomas: a comparative study of 37 cases

Small hepatocellular carcinomas (HCCs), including small and early HCCs (seHCC), small and progressed HCCs (spHCC), are rarely encountered in daily practice. Definite diagnosis is difficult for general pathologists. In this study, we reviewed 1025 cases of HCC and examined for the histologic characteristics of small hepatocellular carcinomas, to facilitate more accurate diagnosis. Slides of archived HCC cases were reviewed by two senior pathologists and small HCC were identified according to the canonical criteria.

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