Altered Electrophysiological Correlates of Motor Inhibition and Performance Monitoring in Tourette’s Syndrome

Tourette's syndrome (TS) is a childhood onset neurodevelopmental disorder characterized by the presence of motor and vocal tics. Tics fluctuate in frequency and intensity; they are sensitive to context and often amplified in exaggerated emotional states. Tics are often preceded by a stressful sensation, the premonitory urge (Leckman et al. 1993). Comorbid disorders are common in TS and prominently include obsessive-compulsive disorder (OCD), attention-deficit hyperactivity disorder (ADHD) and affective disorders (Robertson 2006; Simpson et al.

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