Proton stereotactic radiosurgery for brain metastases: a single institution analysis of 370 patients

There is a paucity of data on the use of proton stereotactic radiosurgery (SRS) for brain metastases. This retrospective study analyzed failure, toxicity, and survival outcomes in 370 patients with 815 metastases treated with proton SRS. To the best of our knowledge, this is the first reported series of proton SRS for treatment of brain metastases and our observations suggest that moderate-dose proton SRS is well-tolerated and can achieve good local control outcomes, comparable to those obtained with conventional SRS strategies.

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