4D cone beam CT-measured target motion underrepresents actual motion

Daily four-dimensional cone beam CT (4DCBCT) provides pre-treatment tumor motion information. We compared the real-time centroid motion of electromagnetic beacons ("target") in the lung with 4DCBCT measurements using two different reconstruction algorithms in combination with internal or external respiratory signals. Our results show that target motion is generally underrepresented in the 4DCBCT scans, and that there is no significant difference between the motion measured in 4DCBCT scans reconstructed using different algorithms and respiratory signals.

https://ift.tt/2r54cTC