Publication date: Available online 8 March 2018
Source:The Spine Journal
Author(s): Caglar Yilgor, Yasemin Yavuz, Nuray Sogunmez, Sleiman Haddad, Anne F. Mannion, Kadir Abul, Louis Boissiere, Ibrahim Obeid, Frank Kleinstück, Francisco Javier Sánchez Pérez-Grueso, Emre Acaroglu, Ferran Pellise, Ahmet Alanay
Background ContextPelvic Tilt (PT) is used as an indicator of pelvic version with increased values indicating retroversion and disability. The concept of using PT solely as an absolute numerical value can be misleading, especially for the patients with Pelvic Incidence (PI) values near the upper and lower normal limits. Relative Pelvic Version (RPV) is a PI-based individualized measure of the pelvic version. RPV indicates the individualized spatial orientation of the pelvis relative to the ideal sacral slope as defined by the magnitude of PI.PurposeThe aim of this study was to compare RPV and PT for their ability to predict mechanical complications and their correlations with HRQoL scores.Study DesignRetrospective analysis of a prospectively collected data of adult spinal deformity patients. Mechanical complications (PJK/PJF, DJK/DJF, rod breakage and implant-related complications) and HRQoL scores (ODI, COMI, SF-36 PCS and SRS-22) were used as outcome measures.MethodsInclusion criteria were ≥4 levels fusion, and ≥2y follow/up. Correlations between PT, RPV, PI and HRQoL were analyzed using Pearson Correlation Coefficient. PI values and mechanical complication rates in RPV subgroups for each PT category were compared using one-way ANOVA, Student's t- and Chi-squared tests. Predictive models for mechanical complications with RPV and PT were analyzed using binomial logistic regressions.Results222 patients (168F, 54M) met the inclusion criteria. Mean age was 52.2±19.3 (18-84) years. Mean follow/up was 28.8±8.2 (24-62) months. There was a significant correlation between PT and PI (r=0.613, p<0.001) threatening the use of PT to quantify pelvic version for different PI values. RPV was not correlated with PI (r=-0.108, p>0.05), being able to quantify pelvic version for all PI values. Compared with PT, RPV had stronger partial correlations with ODI, COMI, SF-36 PCS and SRS-22 scores (p<0.05). Discrimination performance assessed by area under the curve, Percentage Accuracy in Classification, True Positive Rate, True Negative Rate, and Positive and Negative Predictive Values was better for the model with RPV than for PT. For average PI sizes, the agreement between RPV and PT were moderate (=0.609, p<0.001); while the agreement in small and large PI sizes were poor (=0.189, p>0.05; =-0.098, p>0.496, respectively). When analyzed by RPV, each PT '0', '+' and '++' category was further divided into 2 or 3 distinct subgroups of patients having different PI values (p=0.000, p=0.000 and p=0.029, respectively). RPV subgroups within the same PT category displayed different mechanical complication rates (p=0.000, p=0.020 and p=0.019, respectively).ConclusionsPT may be insufficient or misleading in quantifying normoversion for the whole spectrum of PI values when used as an absolute numeric value in conjunction with previously reported population-based average thresholds of 20 and 30 degrees. RPV offers an individualized quantification of ante-, normo- and retroversion for all PI sizes. Schwab PT groups were found to constitute inhomogeneous subgroup of patients with different mean PI values and mechanical complication rates. Compared with PT, RPV showed a greater association with both mechanical complications and HRQoL.
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Πέμπτη 8 Μαρτίου 2018
Relative pelvic version (RPV): an individualized pelvic incidence-based proportional parameter that quantifies pelvic version more precisely than pelvic tilt
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Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
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heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
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