New and emerging techniques for endoscopic treatment of zenker's diverticulum – A state-of-the-art review

Abstract

Zenker's diverticulum (ZD), or pharyngeal pouch, is an anatomical defect characterised by herniation of the posterior pharyngeal wall through Killian's dehiscence, and may result in dysphagia and regurgitation. Multiple therapeutic modalities including surgery, rigid and flexible endoscopy have been developed to manage ZD. Although surgical management with open and endoscopically-assisted techniques have historically been the mainstay of ZD treatment, minimally invasive flexible endoscopic techniques, performed under conscious sedation, are increasingly favoured. Over the last two decades, the advent of new accessories and techniques have changed the landscape of endotherapy for ZD, with the current armamentarium including, but not limited to: endoscopic stapling, CO2 laser, APC, needle knife, bipolar forceps, hook knife, clutch cutter, stag beetle (SB) knife, and submucosal tunnelling endoscopic septum division (STESD). We hereby review the latest evidence to support the endoscopic management of ZD.

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