Ofatumumab for TTP in a Patient with Anaphylaxis Associated with Rituximab

To the Editor: We noted anaphylaxis in a patient with thrombotic thrombocytopenic purpura (TTP), which was associated with human antichimeric antibodies (HACA) to rituximab. Because of the high risk of relapse of TTP, further elective therapy was preferred. Treatment with ofatumumab, a human…

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