Locally Advanced Uterine Cancer: A Multimodality Model or Muddle?

A 54-year-old gravida 3 para 3 postmenopausal woman female has a 1-year history of intermittent vaginal bleeding. Pelvic examination reveals a bulky 6-cm mass at the cervical os obliterating the vaginal fornices. Computed tomography of the abdomen and pelvis shows a heterogeneously enhancing mass in the cervix extending into the lower uterine cavity and vagina, with extensive retroperitoneal lymphadenopathy involving periaortic and aortocaval lymph nodes. The mass is biopsied, and pathology reveals a high-grade carcinoma.

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