Cardiac Morbidity and Radiation Therapy for Breast Cancer

The relationship between radiation treatment for breast cancer and subsequent risk of cardiac morbidity and mortality has been known for decades (1, 2), but risks in the modern era are less clear and seem to be significantly lower than in prior eras (3-5). There have been significant improvements in technology and awareness, allowing more nuanced dosimetric analysis and attention to cardiac exposure in patients treated with modern computed tomography (CT)–based planning, but long-term follow-up with more modern techniques is limited.

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