MRI-guided adaptive radiotherapy; a “game changer” for prostate radiotherapy

Radiotherapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. With a low estimated alpha/beta ratio, a larger dose per fraction would be beneficial, with moderate fractionation schedules rapidly becoming a standard of care. The integration of a magnetic resonance imaging (MRI) scanner and linear accelerator (linac) allows accurate soft tissue tracking with the capacity to re-plan for the anatomy of the day. Extreme hypofractionation schedules become a possibility using the potentially automated steps of autosegmentation, MR-only workflow and real-time adaptive planning.

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