Micelles: Multifunctional Polymeric Micelles for Combining Chelation and Detection of Iron in Living Cells (Adv. Healthcare Mater. 17/2017)

May P. Xiong and co-workers construct multifunctional Pluronics F127 micelles for iron chelation and fluorescence detection by introducing tetraphenylethene and the chelating drug deferoxamine into self-assembling polymeric micelles in article 1700162. Deferoxamine can simultaneously be used to chelate iron(III) and quench the fluorescence emission of tetraphenylethene. This fluorescence "turn-off" process can be used to monitor the iron chelation process in an iron overload cell model.

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