Identification of patients with localized Ewing sarcoma at higher risk for local failure: A report from the Children’s Oncology Group

Our analysis of local tumor control outcomes in 956 Ewing sarcoma patients demonstrates age ≥18 years and use of definitive radiotherapy, primarily for pelvis and extremity tumors, are associated with the highest risk of local failure. Local tumor control is excellent and similar between surgery and definitive radiotherapy for axial non-spine, spine, and soft tissue extraskeletal tumors.

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