Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes

Wu and colleagues show that engineered epidermal progenitor cells can function as a gene therapy vehicle. Using an immunocompetent skin transplantation model, they show skin grafts that secrete GLP-1 in a controllable manner can normalize body weight and blood glucose levels in diet-induced obese and diabetic mice.

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