Performance of knowledge-based radiation therapy planning for the glioblastoma disease site

A knowledge-based radiation therapy planning model for glioblastoma was created using RapidPlanTM (Varian). 82 patients treated with 60 Gy to the target in 30 fractions were used to train the model. The model was validated on an independent set of 45 patients. The plans created by the model had superior planning target volume dose metrics compared to the manual planning, improved optic apparatus sparing, and order of magnitude reduction in planning time.

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