Language and motor function thresholds during pediatric extra-operative electrical cortical stimulation brain mapping

Safe neurosurgical resection of the seizure-onset zone requires localization of language and motor cortices in each individual patient. Electrical cortical stimulation (ECS) is the standard technique for brain mapping with intracranial electrodes. However, it has been shown that in pediatric patients, particularly younger than 10 years of age, ECS may often fail to identify language cortex (Schevon et al., 2007). ECS supposedly creates a transient reversible functional interference to localize critical cortical sites, and has been shown to predict post-operative outcomes (Hermann et al., 1988; Hermann et al., 1999).

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