After-discharges and seizures during pediatric extra-operative electrical cortical stimulation functional brain mapping: incidence, thresholds, and determinants

Electrical cortical stimulation (ECS) is the standard method for pre-surgical mapping of cortical function, particularly language and motor cortices, to optimize safety and efficacy of epilepsy surgery. However, ECS is known to be associated with the risks of after-discharges (ADs) and seizures, with several neurophysiological implications (Jayakar et al., 2008). ADs can potentially evolve into electrographic or electro-clinical seizures, even when the stimulated brain region is not known to generate spontaneous seizures (Blume et al., 2004).

http://ift.tt/2tEyYB5