Subclinical white matter lesions and medial temporal lobe atrophy are associated with EEG slowing in a memory clinic cohort

As the world's population ages, the identification of subjects at increased risk of Alzheimer's dementia and the early detection of Alzheimer's disease (AD) are key topics in research and are also of increasing relevance in clinical care and patient counselling. Newly refined diagnostic criteria for AD now better define clinical phenotype and integrate neuroimaging and cerebrospinal fluid biomarkers into the diagnostic process. They cover the full staging of the disease from the subjective cognitive impairment (SCI) and mild cognitive impairment (MCI) to clinically obvious dementia (Dubois et al., 2014).

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