Issue Highlights

Cross-sectional studies and clinical experience suggest there is a higher prevalence of depression and anxiety in patients with functional gastrointestinal diseases (FGID). To what extent this reflects the impact of disease symptoms on mood and whether mood disorders precede and may indeed be causally implicated in the pathogenesis of FGID has not been well established. In this issue of Clinical Gastroenterology and Hepatology, Jones et al present a study that examined the bidirectional association between mood disorders and FGID in two population-based databases.

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