Nutrients, Vol. 11, Pages 2829: Investigation of Antibacterial and Antiinflammatory Activities of Proanthocyanidins from Pelargonium sidoides DC Root ExtractNutrients, Vol. 11, Pages 2829: Investigation of Antibacterial and Antiinflammatory Activities of Proanthocyanidins from Pelargonium sidoides DC Root Extract Nutrients doi: 10.3390/nu11112829 Authors: Aiste Jekabsone Inga Sile Andrea Cochis Marina Makrecka-Kuka Goda Laucaityte Elina Makarova Lia Rimondini Rasa Bernotiene Lina Raudone Evelina...
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Medicina, Vol. 55, Pages 750: Concurrent Validity of the Foot Health Status Questionnaire and Study Short Form 36 for Measuring the Health-Related Quality of Life in Patients with Foot ProblemsMedicina, Vol. 55, Pages 750: Concurrent Validity of the Foot Health Status Questionnaire and Study Short Form 36 for Measuring the Health-Related Quality of Life in Patients with Foot Problems Medicina doi: 10.3390/medicina55110750 Authors: Patricia Palomo-López Daniel López-López Ricardo Becerro-de-Bengoa-Vallejo...
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Gastrointestinal Disorders,GastrointestDisord, Vol. 1, Pages 391-402: Role of Gastric Emptying in Symptoms of GastroparesisGastrointestDisord, Vol. 1, Pages 391-402: Role of Gastric Emptying in Symptoms of Gastroparesis Gastrointestinal Disorders doi: 10.3390/gidisord1040032 Authors: Jehangir Parkman The symptoms of gastroparesis, such as nausea, vomiting, postprandial fullness, early satiety and abdominal pain, frequently impair the quality of life of the affected individuals. The diagnosis of...
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Antibiotics, Vol. 8, Pages 229: Effectiveness of Efflux Pump Inhibitors as Biofilm Disruptors and Resistance Breakers in Gram-Negative (ESKAPEE) BacteriaAntibiotics, Vol. 8, Pages 229: Effectiveness of Efflux Pump Inhibitors as Biofilm Disruptors and Resistance Breakers in Gram-Negative (ESKAPEE) Bacteria Antibiotics doi: 10.3390/antibiotics8040229 Authors: Reza Sutton Rahman Antibiotic resistance represents a significant threat to the modern healthcare provision. The ESKAPEE pathogens (Enterococcus...
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Prophylactic use of exogenous melatonin and melatonin receptor agonists to improve sleep and delirium in the intensive care units: a systematic review and meta-analysis of randomized controlled trialsAbstract To investigate the efficacy of exogenous administration of melatonin and melatonin receptor agonists for the improvement of delirium, sleep, and other clinical outcomes of subjects in the intensive care unit (ICU). We carefully searched three electronic databases, i.e., Pubmed/Medline, Embase,...
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No effect of electrical transcranial direct current stimulation adjunct treatment for epilepsia partialis continua in POLG disease.Related ArticlesNo effect of electrical transcranial direct current stimulation adjunct treatment for epilepsia partialis continua in POLG disease. Epilepsy Behav Rep. 2019;12:100339 Authors: Marquardt L, Eichele T, Bindoff LA, Olberg HK, Veiby G, Eichele H, Kusztrits I, Hirnstein M Abstract We report a 15-year-old female with POLG-related mitochondrial disease who developed...
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Relationship between video head impulse test, ocular and cervical vestibular evoked myogenic potentials, and compartmental magnetic resonance imaging classification in menière's diseaseObjectives/Hypothesis Currently, it is possible to assess in vivo the morphology of each compartment of the endolymphatic spaces 4 hours after an intravenous administration of gadolinium on magnetic resonance imaging (MRI). The aim of this study was to assess the correlation between otolithic and ampullar functions...
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Dental Changes In Children With Congenital Zika SyndromeAbstract Objective To describe oral alterations in children with Congenital ZikaSyndrome (CZS). Methods This was acase series, whose research instrument was a structured questionnaire, associated with the use of medical record data and extra and intraoral clinical examination. Results 32 children were evaluated, the majority male (18/32%‐56.3%), mean age22 months (SD = 2.71). It was also observed that the majority of the patients (19/32%‐59.4%)...
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Ozagrel for Postoperative Management of Aneurysmal Subarachnoid HemorrhagesVinayak Narayan, Dhaval Shukla, Dhananjaya I Bhat, AR Prabhuraj, Bhagavatula I DeviNeurology India 2019 67(5):1286-1289 Background: A number of pharmacological agents have been tried to circumvent the problem of delayed cerebral ischemia (DCI) with ozagrel sodium being one such agent aimed at the prevention of DCI. Ozagrel is an inhibitor of thromboxane synthetase. It has anti-platelet aggregation action and it dilates vessels....
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A Comparison of Two LDL Cholesterol Targets after Ischemic StrokeIntensive therapy to lower serum lipid levels with the use of statins is recommended after transient ischemic attack (TIA) or ischemic stroke of atherosclerotic origin. These recommendations are based on the results of the Stroke Prevention by Aggressive Reduction in Cholesterol Level (SPARCL)…The New England Journal of Medicine: Neurology\NeurosurgeryMon Nov 18, 2019 02:00Statins and Stroke — It's ComplicatedNew England Journal of...
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Tumor-induced Osteomalacia due to a Phosphaturic Mesenchymal Tumor in the Cervical Spine: A Case Report and Literature ReviewNitish Agarwal, Shashank S Kale, Kalpana KumariNeurology India 2019 67(5):1334-1340 Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome of certain mesenchymal tumors which secrete fibroblast growth factor-23 (FGF-23) responsible for causing features of hypophosphatemia and osteomalacia in these patients. Most of them involve the appendicular skeleton and occasionally...
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Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow.Related ArticlesPneumococcus Infection of Primary Human Endothelial Cells in Constant Flow. J Vis Exp. 2019 Oct 31;(152): Authors: Jagau H, Behrens IK, Steinert M, Bergmann S Abstract Interaction of Streptococcus pneumoniae with the surface of endothelial cells is mediated in blood flow via mechanosensitive proteins such as the Von Willebrand Factor (VWF). This glycoprotein changes its molecular conformation in response to...
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Immune checkpoint inhibitor-induced sarcoidosis-like granulomas.Related ArticlesImmune checkpoint inhibitor-induced sarcoidosis-like granulomas. Int J Clin Oncol. 2019 Oct;24(10):1171-1181 Authors: Rambhia PH, Reichert B, Scott JF, Feneran AN, Kazakov JA, Honda K, Koon H, Gerstenblith MR Abstract Immune checkpoint inhibitors targeting the cytotoxic T lymphocyte-associated antigen-4 and programmed cell death-1 receptors have transformed the treatment of melanoma and other cancers. These therapies...
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Auditory cortex responses to interaural time differences in the envelope of low-frequency sound, recorded with MEG in young and older listeners.Related ArticlesAuditory cortex responses to interaural time differences in the envelope of low-frequency sound, recorded with MEG in young and older listeners. Hear Res. 2018 12;370:22-39 Authors: Ross B Abstract Interaural time and intensity differences (ITD and IID) are important cues in binaural hearing and allow for sound localization, improving speech...
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Attention and inhibitory control deficits in patients with genetic generalized epilepsy and psychogenic nonepileptic seizure.Related ArticlesAttention and inhibitory control deficits in patients with genetic generalized epilepsy and psychogenic nonepileptic seizure. Epilepsy Behav. 2019 Nov 15;102:106672 Authors: Simani L, Roozbeh M, Rostami M, Pakdaman H, Ramezani M, Asadollahi M Abstract This study aimed to evaluate the attention and inhibitory control functions in patients with genetic generalized...
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Simultaneous Changes in Abdominal Adipose and Muscle Tissues Following Treatments by High-Intensity Focused Electromagnetic (HIFEM) Technology-Based Device: Computed Tomography EvaluationRelated ArticlesSimultaneous Changes in Abdominal Adipose and Muscle Tissues Following Treatments by High-Intensity Focused Electromagnetic (HIFEM) Technology-Based Device: Computed Tomography Evaluation J Drugs Dermatol. 2019 Nov 01;18(11):1098-1102 Authors: Kent DE, Jacob CI Abstract Objective: This study investigates...
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Co-Occurring Psychosocial Problems and Multiple Sexual Partners among Men Who Have Sex with Men in Shanghai, China: A Syndemic Approach.Related ArticlesCo-Occurring Psychosocial Problems and Multiple Sexual Partners among Men Who Have Sex with Men in Shanghai, China: A Syndemic Approach. J Sex Res. 2018 09;55(7):892-901 Authors: Wang Z, Zhao X, Zhang Z, Luo M, Shen Q, Dong Y, Wang Y, Cai Y Abstract We aimed to apply syndemic theory to verify the association and reinforcing effects between psychosocial...
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Epidermal Carcinoma of the Conchal Bowl: Creation of a Multidisciplinary Pathway ApproachJournal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundMalignant neoplasms of the auricle make up 6% of all skin cancers. Management of cutaneous neoplasms of the conchal bowl presents a unique challenge in visualizing and defining margins that may extend into the external auditory canal (EAC).ObjectivesThe objective of this study was to create a multidisciplinary pathway for cutaneous carcinoma...
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The top 100 most influential articles in allergic rhinitis from 1970 to 2018: A bibliometric analysisJournal of International Medical Research, Ahead of Print.SAGE-Journals: Journal of International Medical Research: Table of ContentsTue Nov 19, 2019 13:40Process of ectopic tooth formation in the maxillary sinus: follow-up observation of one caseJournal of International Medical Research, Ahead of Print.SAGE-Journals: Journal of International Medical Research: Table of ContentsTue Nov 19, 2019 13:33Risk...
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The Crucial Role of CXCL8 and Its Receptors in Colorectal Liver MetastasisCXCL8 (also known as IL-8) can produce different biological effects by binding to its receptors: CXCR1, CXCR2, and the Duffy antigen receptor for chemokines (DARC). CXCL8 and its receptors are associated with the development of various tumor types, especially colorectal cancer and its liver metastases. In addition to promoting angiogenesis, proliferation, invasion, migration, and the survival of colorectal cancer (CRC) cells,...
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Enhanced Ex Vivo Generation of Erythroid Cells from Human Induced Pluripotent Stem Cells in a Simplified Cell Culture System with Low Cytokine SupportStem Cells and Development, Ahead of Print.Stem Cells and Development07:52Residual Diploidy in Polyploid Tissues: A Cellular State with Enhanced Proliferative Capacity for Tissue Regeneration?Stem Cells and Development, Ahead of Print.Stem Cells and DevelopmentTue Nov 19, 2019 19:44Estrogen facilitates gastric cancer cell proliferation and invasion...
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Exploring Medical Students' Perceptions of Organ Procurement: Need for a Formalized Medical Student CurriculumPublication date: Available online 18 November 2019Source: Journal of Surgical EducationAuthor(s): Leah K. Winer, Matthew P. Vivero, Brendan F. Scully, Alexander R. Cortez, Al-Faraaz Kassam, Roman Nowygrod, Adam D. Griesemer, Jean C. Emond, Ralph C. QuillinObjectiveWe evaluated the medical student experience with a deceased-donor multiorgan procurement program at a single center. The program...
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New species and new records of camallanid nematodes (Nematoda, Camallanidae) from marine fishes and sea snakes in New CaledoniaAuthors: František Moravec and Jean-Lou Justine.<br />Parasite Vol. 26 , page 66<br />Published online: 20/11/2019<br /> Keywords: Nematoda ; Helminth parasite ; Camallanoidea ; Aulopiformes ; Carcharhiniformes ; Perciformes ; Pleuronectiformes ; Serpentes ; South Pacific.<img src="http://feeds.feedburner.com/~r/edp_parasite/~4/LxZHAwABqzA" height="1"...
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A Ferret Model of Inflammation-sensitized Late Preterm Hypoxic-ischemic Brain InjuryThe method describes inflammation-sensitized hypoxic-ischemic and hyperoxic brain injury in the P17 ferret to model the complex interaction between prolonged inflammation and oxidative brain injury experienced in a number of late preterm infants.JoVE: Journal of Visualized ExperimentsTue Nov 19, 2019 19:00Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality...
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[Reninoma: A Rare Cause of Endocrine Hypertension].Related Articles[Reninoma: A Rare Cause of Endocrine Hypertension]. Acta Med Port. 2019 May 08;: Authors: Marques B, Couto J, Lemos MC, Rodrigues F Abstract Juxtaglomerular tumours are rare causes of secondary hypertension. They typically present with difficult-to-manage hypertension, hypokalemia, hyperreninemia and secondary hyperaldosteronism. The authors describe a clinical case of a 45 years old female patient, with personal history of difficult-to-manage...!@...
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Author Correction: A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutationNature Communications, Published online: 20 November 2019; doi:10.1038/s41467-019-13379-9Author Correction: A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutationNature Communications - current - nature.com science feeds02:00Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative...
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Alterations in the Levels of Growth Factors in Adolescents with Major Depressive Disorder: A Longitudinal Study during the Treatment with FluoxetineMajor depressive disorder (MDD) has a prevalence of 5% in adolescents. Several studies have described the association between the inflammatory response and MDD, but little is known about the relationship between MDD and growth factors, such as IL-7, IL-9, IL-17A, VEGF, basic FGF, G-CSF, and GM-CSF. It must be appointed that there are scarce reports on...
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Characterization of long non-coding RNA and messenger RNA profiles in laryngeal cancer by weighted gene co-expression network analysis.Related ArticlesCharacterization of long non-coding RNA and messenger RNA profiles in laryngeal cancer by weighted gene co-expression network analysis. Aging (Albany NY). 2019 Nov 18;11: Authors: Liu H, Sun Y, Tian H, Xiao X, Zhang J, Wang Y, Yu F Abstract Laryngeal cancer (LC) is a malignant tumor in the head and neck region. It was recently elucidated that long...
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"Confessions of a Reluctant Caregiver" Palliative Educational Program: The Results of a Survey Assessing Physicians' Perceptions of Drama-Based Education for End-of-Life CareAbstract Inadequate palliative care training in medical education is associated with many physicians feeling unprepared to care for dying patients and their families. Therefore, an opportunity exists to offer physicians continuing medical education that increases their understanding of and comfort with complex palliative care...
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Knowledge of and Utilization of Emergency Contraceptive and Its Associated Factors among Women Seeking Induced Abortion in Public Hospitals, Eastern Tigray, Ethiopia, 2017: A Cross-Sectional StudyBackground. In developing countries, most maternal deaths are related to the lack of accessibility and availability of reproductive health services. In those nations, emergency contraceptive pills are the most commonly used family planning methods to prevent unintended pregnancy. However, women do not use...
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Luminescent gold nanoclusters for in vivo tumor imagingAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01598A, Tutorial ReviewHuili Li, Hongle Li, Ajun WanFluorescence gold nanoclusters (AuNCs) are emerging as novel imaging contrast agents. These molecules offer excellent prospects for non-invasive tumor diagnosis strategies because of their ultra-small size, tunable emissions from the...The content of this RSS Feed (c) The Royal Society of ChemistryRoyal Society of Chemistry (Great Britain) Society...
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Highlights and recent developments in skin allergy and related diseases in EAACI journals (2018)The European Academy of Allergy and Clinical Immunology (EAACI) supports three journals: Allergy, Paediatric Allergy and Immunology as well as Clinical and Translational Allergy. The major goals of EAACI inclu...Allergy02:00Illness perceptions in difficult to treat asthma compared with a depressed psychosis cohortBeliefs about one's illness or "illness perceptions", such as severity, chronicity or degree...
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Παραδοσιακές σούπες με ισχυρή φαρμακευτική δράσηΚάποιες από τις παραδοσιακές χορτόσουπες και κρεατόσουπες μπορούν να διαταράξουν τον κύκλο ζωής του Plasmodium falciparum, του πιο θανατηφόρου παράσιτου της ελονοσίας, όπως αποκαλύπτουν τα αποτελέσματα της πρώτης σχετικής μελέτης, που δημοσιεύθηκε στο Archives of Disease in Childhood. Δεδομένου ότι η ελονοσία αποτελεί κίνδυνο για τον μισό παγκόσμιο πληθυσμό και ότι η αντίσταση στα φάρμακα που χρησιμοποιούνται για τη θεραπεία της συνεχίζει να αναπτύσσεται,...
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Management of the airway in intensive carePublication date: Available online 25 October 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Miles Beeny, Arno CrousAbstractAirway management in the intensive care unit (ICU) is largely uneventful; there is a higher incidence of airway difficulties, however, than those encountered in the operating suite. Management of the airway in the ICU presents challenges unique to this environment that must be coped with by a multidisciplinary team that...
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In vitro fermentation profile of soluble dietary fibers obtained by different enzymatic extractions from barley branPublication date: Available online 14 November 2019Source: Bioactive Carbohydrates and Dietary FibreAuthor(s): Reza Karimi, Mohammad Hossein Azizi, Mohammad Ali Sahari, Ahmad Enosh KazemAbstractThe purpose of this study was to compare the fermentative properties of enzymatically extracted barley bran dietary fibers using a batch in vitro fecal fermentation method. Fibers with different...
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Where is the brain in all of this?Moving forward the in vivo diagnosis of the synucleinopathiesDysautonomia in the synucleinopathies: not just orthostatic hypotensionEarly bladder dysfunction in multiple system atrophy: who seek shall findMultiple system atrophy: a disorder targeting the brainstem control of survivalAssociation of innervation-adjusted alpha-synuclein in arrector pili muscles with cardiac noradrenergic deficiency in autonomic synucleinopathiesAbstractBackgroundAutonomic synucleinopathies...
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Intraoperative Oxidative Damage and Delirium after Cardiac SurgeryMarcos G. Lopez, M.D., M.S.; Christopher G. Hughes, M.D., M.S.; Anthony DeMatteo, B.S.; Jason B. O'Neal, M.D.; J. Brennan McNeil, B.S.; et alMatthew S. Shotwell, Ph.D.; Jennifer Morse, M.S.; Michael R. Petracek, M.D.; Ashish S. Shah, M.D.; Nancy J. Brown, M.D.; Frederic T. Billings, IV, M.D., M.Sc. Author NotesFrom the Divisions of Anesthesiology Critical Care Medicine (M.G.L., C.G.H., F.T.B.) and Cardiothoracic Anesthesiology (J.B.O.,...
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Bedside Evaluation of Pulmonary Embolism by Electrical Impedance TomographyLuigi G. Grassi, M.D.; Roberta Santiago, M.D., Ph.D.; Gaetano Florio, M.D.; Lorenzo Berra, M.D. Author NotesFrom the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.Correspondence: Address correspondence to Dr. Berra: lberra@mgh.harvard.eduAnesthesiology Newly Published on November 18, 2019. doi:https://doi.org/10.1097/ALN.0000000000003059Electrical...
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La photo chimiothérapie extra-corporelle ; hier, aujourd'hui et demainPublication date: Available online 18 November 2019Source: Annales de Dermatologie et de VénéréologieAuthor(s): F. HeshmatiNodules scabieux de la verge chez un enfantPublication date: Available online 12 November 2019Source: Annales de Dermatologie et de VénéréologieAuthor(s): F. Frikha, E. Bahloul, K. Sellami, M. Amouri, H. TurkiRéponse des auteurs à la correspondance à propos de l'article : « Place de l'Androcur® dans le traitement...
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Reducing Repeat Offending Through Less Prosecution in Victoria, Australia: Opportunities for Increased Diversion of OffendersAbstractResearch QuestionHow did the use of diversion from prosecution and criminal sentencing change in Victoria, Australia, in the 10 years to 2016/2017, with what estimated effects on repeat offending?DataWe tracked 1,163,113 criminal cases brought against both juveniles and adults by police in the state of Victoria, Australia, including 181,836 diversions, during the 10-year...
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Mitochondrial connexin 43 in sex-dependent myocardial responses and estrogen-mediated cardiac protection following acute ischemia/reperfusion injuryAbstractPreserving mitochondrial activity is crucial in rescuing cardiac function following acute myocardial ischemia/reperfusion (I/R). The sex difference in myocardial functional recovery has been observed after I/R. Given the key role of mitochondrial connexin43 (Cx43) in cardiac protection initiated by ischemic preconditioning, we aimed to determine...
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Alexandra Cox: Trapped in a Vice: The Consequences of Confinement for Young PeopleAn amendment to this paper has been published and can be accessed via a link at the top of the paperCorrection to: Understanding the Buffering Effects of Protective Factors on the Relationship between Adverse Childhood Experiences and Teen Dating Violence PerpetrationAn amendment to this article has been published and can be accessed via a link at the top of the article.Sarah Halpern-Meekin: Social Poverty: Low-Income...
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Multiplayer Pursuit-Evasion Games in Three-Dimensional Flow FieldsUnfortunately, the acknowledgement text was not submitted during the acceptance of the manuscript.Preface to the Focused Issue on Dynamic Games in Cyber SecurityIterative Computation of Security Strategies of Matrix Games with Growing Action SetAbstractThis paper studies how to efficiently update the saddle-point strategy, or security strategy of one player in a matrix game when the other player develops new actions in the game. It...
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Opioids and the Predilection for Violence in the Pain Clinic: A Physician's PerspectiveAbstractPain physicians, more so than any other specialty, interact with a patient population that is significantly more likely to engage in violence. In this commentary on the article "Patient-on-Provider Violence in the Pain Clinic" by Judy George, we echo some of the points mentioned in the manuscript. There needs to be a better system in place to identify and to deal with problem patients seeking drugs. Although...
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Inverse association between changes in energetic cost of walking and vertical accelerations in non-metastatic breast cancer survivorsAbstractPurposeWith accelerometry, the utility to detect changes in physical activity are predicated on the assumption that walking energetics and gait mechanics do not change. The present work examined associations between changes (∆) in walking energetics, exercise self-efficacy, and several accelerometer-derived metrics.MethodsSecondary analyses were performed among...
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Spatiotemporal clustering of suicides in the US from 1999 to 2016: a spatial epidemiological approachAbstractPurposeThis study aims to describe and characterize the spatial and temporal clustering patterns of suicide in the ten states with the greatest suicide burden in the United States from 1999 to 2016.MethodsAll suicide deaths from January 1, 1999 to December 31, 2016 in the United States were identified using data from the Wide-ranging Online Data for Epidemiologic Research (WONDER) dataset....
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Level and change in economic, social, and personal resources for people retiring from paid work and other labour market statusesAbstractWell-being in retirement is thought to depend on person's level of resources and how his or her resources change during retirement. However, to date few studies have directly investigated resource trajectories during retirement. The current study therefore examines how economic, personal, and social-relational resources change during the retirement transition for...
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The Role of Executive Function in Predicting Children's Outcomes in a Cognitive Behavioral Treatment for Trauma-Related Nightmares and Secondary Sleep DisturbancesAbstractPredictors of children's outcomes in trauma-focused interventions are well documented. However, little is known about the role of higher-order cognitive processes, specifically executive function (EF) abilities, in determining children's responses to treatments specifically for trauma-related sleep disturbances. EF is independently...
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Rights as Relationships: Collaborating with Faith Healers in Community Mental Health in GhanaAbstractThis paper explores the ways in which mental health workers think through the ethics of working with traditional and faith healers in Ghana. Despite reforms along the lines advocated by global mental health, including rights-based legislation and the expansion of community-based mental health care, such healers remain popular resources for treatment and mechanical restraint and other forms of coercion...
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Introducing "Classics in Biological Theory"Referees for Volume 14 (Issues 1–4), 2019A New , New Definition of Evolution by Natural SelectionAbstractThis note provides a definition of evolution by natural selection that is compatible with the extended evolutionary synthesis.Reciprocal Causation and the Extended Evolutionary SynthesisAbstractKevin Laland and colleagues have put forward a number of arguments motivating an extended evolutionary synthesis. Here I examine Laland et al.'s central concept...
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The elusive sources of legitimacy beliefs: Civil society views of international election observersAbstractWhen do members of civil society view international election observers as legitimate? Motivated by recent work on the legitimacy of international organizations, we evaluate what type of information affects non-governmental organizations' (NGOs) beliefs about international election observer groups, which include both intergovernmental organizations (IGOs) and international non-governmental organizations...
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Investigating Evolutionary Rate Variation in BacteriaAbstractRates of molecular evolution are known to vary between species and across all kingdoms of life. Here, we explore variation in the rate at which bacteria accumulate mutations (accumulation rates) in their natural environments over short periods of time. We have compiled estimates of the accumulation rate for over 34 species of bacteria, the majority of which are pathogens evolving either within an individual host or during outbreaks. Across...
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Neues aus der Onkologie,Liebe Leserinnen und Leser, dieser Newsletter steht ganz im Zeichen des ESMO-Kongresses, der Ende September in Barcelona stattfand. Auf der Jahrestagung der europäischen Krebsgesellschaft wurden wieder zahlreiche und interessante Studiendaten vorgestellt.So berichtet Prof. Mahner über aktuelle Entwicklungen in der Therapie des Ovarialkarzinoms mit PARP-Inhibitoren. Auch beim Mammakarzinom ist viel in Bewegung, wie Prof. Lüftner erläutert.Weitere Interviews etwa zu neuen Daten...
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Superior Trunk Block versus Interscalene Block, When interscalene block was compared with superior trunk block, less frequent hemidiaphragmatic paralysis was seen in the superior trunk block group. Superior trunk block was noninferior to interscalene block in terms of pain scores for up to 24 h postoperatively, and superior trunk block patients were no less satisfied. FREEF19n the Infant BrainIn infants younger than four months, slow wave functional connectivity breaks...
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STrategically Acquired Gradient Echo (STAGE) imaging, part III: Technical advances and clinical applications of a rapid multi-contrast multi-parametric brain imaging methodPublication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): E. Mark Haacke, Yongsheng Chen, David Utriainen, Bo Wu, Yu Wang, Shuang Xia, Naying He, Chunyan Zhang, Xiao Wang, M. Marcella Lagana, Yu Luo, Ali Fatemi, Saifeng Liu, Sara Gharabaghi, Dongmei Wu, Sean K. Sethi, Feng Huang, Taotao Sun, Feifei Qu,...
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Ayushman Bharat Pradhan Mantri Jan Arogya Yojana (AB PMJAY): Hope for Millions and Exciting New Prospects for Neuro-HealthcareVinod PaulNeurology India 2019 67(5):1186-1187Tantra and Modern Neurosciences: Is there any Correlation?Anand Venkatraman, Rajarshi Nandy, Shyam Sudarshan Rao, Darshan Hemendra Mehta, Anand Viswanathan, Rama JayasundarNeurology India 2019 67(5):1188-1193Background and Aims: Many studies have conclusively proven that meditative techniques derived from the Indian systems of...
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Assessment of sealing ability of two root-end filling materials at different depths: A comparative studyAnupama Ahirwar, J John, Midhun Paul, Allu Baby, Bilu Sara, Sapna C KambirandaInternational Journal of Oral Care and Research 2019 7(3):61-64Background: Most biocompatible and least microleakage of root-end filling material helps the clinician to provide a proper apical seal that prevents the movement of bacteria and the spreading of their remnants from the root canal system into the periapical...
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Association of vitamin D with diabetic neuropathy among Sudanese patients with type 2 diabetes mellitusIbrahim Wagea Alla Dalia, M Abdalla Abdelmula, Abdelrahman Elbashir Zeinab, A Abdrabo AbdElkarimNigerian Journal of Basic and Clinical Sciences 2019 16(2):79-82Background: Neuropathy is a common diabetic microvascular complication which reduces quality of life; causing pain and irritation in lower limbs and may result in amputation. Several Studies documented that vitamin D deficiency have extra...
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Expression patterns of cofilin and scinderin in breast cancer and their association with clinicopathological features in Iranian patientsParisa Nourmohammadi, Mojtaba Saffari, Mohammad Hasan Sheikhha, Sara Tutunchi, Bahareh Nourmohammadi, Amirnader Emami Razavi, Reza Shirkoohi, Nasrin GhasemiClinical Cancer Investigation Journal 2019 8(6):215-221Background: Cofilin-1 (CLF1) and scinderin (SCIN) are significant actin-binding proteins that are involved in the regulation of the actin polymerization...
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Diagnostic Value of Acoustic and Aerodynamic Measurements in Vocal Fold Movement Disorders and their Correlation with Laryngeal Electromyography and Voice Handicap IndexInvestigate the relationships between the Voice Handicap Index, laryngeal electromyography, and objective acoustic voice testing in order to determine the utility of these measures in the management of vocal fold movement disorders.Tongue Edema Secondary to Suspension LaryngoscopySuspension microlaryngoscopy (SML) is generally a safe,...
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Radiocesium (137Cs) concentrations in the two-toed amphiuma (Amphiuma means) and the lesser siren (Siren intermedia)Publication date: March 2020Source: Journal of Environmental Radioactivity, Volume 213Author(s): David L. Haskins, Albert L. BryanAbstractThis study sought to determine radiocesium (137Cs) concentrations in two species of aquatic salamanders – the two-toed amphiuma (Amphiuma means) and the lesser siren (Siren intermedia) on the Savannah River Site. Concentrations (137Cs Bq/g, dry wt)...
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Observed dependence of surface ozone on increasing temperature in Shanghai, ChinaPublication date: 15 January 2020Source: Atmospheric Environment, Volume 221Author(s): Yixuan Gu, Ke Li, Jianming Xu, Hong Liao, Guangqiang ZhouAbstractEight-year measurements at urban (Xujiahui, XJH) and remote (Dongtan, DT) sites during time period 2010–2017 are employed to examine the surface ozone (O3)-temperature relationship in Shanghai, China. O3 pollution was getting worse in Shanghai, with daily maximum O3 concentrations...
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Gerontology is essential to the identity of geriatric medicineHighlights of the 14th International Congress of the European Geriatric Medicine SocietyKey summary pointsAimTo report the most important messages of the 2018 EuGMS Congress in Berlin.FindingsFrom social issues to nutrition, from cardiovascular aspects to new definition of sarcopenia, the congress has informed more than 1800 participants on the hottest issues of geriatric medicine of today.MessageThe EuGMS congress brings together both...
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"Patient Registries: An Underused Resource for Medicines Evaluation: Operational Proposals for Increasing the Use of Patient Registries in Regulatory Assessments"Authors' Reply to Ravi Jandhyala's Comment on "Patient Registries: An Underused Resource for Medicines Evaluation: Operational Proposals for Increasing the Use of Patient Registries in Regulatory Assessments"Recommendations for the Use of Social Media in Pharmacovigilance: Lessons from IMI WEB-RADRAbstractOver a period of 3 years, the European...
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Yujin Nagasawa: Maximal god: a new defense of perfect being theismSynthesizing Aquinas and Newman on religionAbstractIn this paper I carry out a philosophical inquiry that yields an account of religion as a personal disposition. This exercise is also expository, since I take my bearings from two thinkers, Thomas Aquinas and John Henry Newman. Regarding Aquinas, this means delineating his treatment of the virtue of 'religio' in the 'Summa theologiae'; regarding Newman, it means attending to his description...
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To be capsulated or not be capsulated: that is the GAS questionDuodenoscope-associated infections: a reviewAbstractFlexible digestive endoscopes are used for the management of various conditions with hundreds of thousands of therapeutic procedures performed worldwide each year. Duodenoscopes are indispensable tools for the delivery of minimally invasive vital care of numerous pancreaticobiliary disorders. Despite the fact that nosocomial infections after endoscopic retrograde cholangiopancreatography...
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Designing and validating a PVA liver phantom with respiratory motion for needle-based interventionsAbstractPurposeThe purpose is to design and validate an anthropomorphic polyvinyl alcohol (PVA) liver phantom with respiratory motion to simulate needle-based interventions. Such a system can, for example, be used as a validation tool for novel needles.MethodsImage segmentations of CT scans of four patients during inspiration and expiration were used to measure liver and rib displacement. An anthropomorphic...
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Stand der interkulturellen Öffnung der Einrichtungen im Pflegebereich in BerlinZusammenfassungHintergrundIn Zeiten des demografischen Wandels in Deutschland kann die Prognose gestellt werden, dass immer mehr ältere Migrant*innen ins System der Altenhilfe und Altenpflege rücken werden. Es ist aber festzustellen, dass viele Migrant*innen migrationsbedingte Barrieren bei der Inanspruchnahme der Pflege- und Versorgungsangebote haben. Die interkulturelle Öffnung der pflegerischen Einrichtungen soll die...
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LMNA-Related Muscular Dystrophy with Clinical Intrafamilial VariabilityAbstractThe LMNA gene is associated to a huge broad of phenotypes, including congenital Emery-Dreifuss muscular dystrophy and late-onset LMNA-related muscular dystrophy. In these forms, muscle weakness, contractures, and cardiac impairment are common. In an autosomal dominant pedigree including 5 affected patients, NGS molecular analysis performed in 6 relatives identifies the heterozygous c.1129C>T p.Arg377Cys variant in the...
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Adamts17 is involved in skeletogenesis through modulation of BMP‑Smad1/5/8 pathwayIn the published article, the Fig. 4a was published incorrectly.Concerns regarding Baksa B, Kovacs A, Bayasgalan T, Szentesi P, Koseghy A, Szucs P, Balazs P. Characterization of functional subgroups among genetically identified cholinergic neurons in the pedunculopontine nucleus. Cell Molec. Life Sci. 2019-04-02Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathwayAbstractFibrillin microfibrils...
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Longitudinal Analysis of the Choriocapillaris Using Optical Coherence Tomography Angiography Reveals Subretinal Fluid as a Substantial Confounder in Patients with Acute Central Serous ChorioretinopathyAbstractIntroductionTo describe the influence of subretinal fluid (SRF) in analysis of the flow signal from the choriocapillaris (CC) via optical coherence tomography angiography (OCTA) in patients with acute central serous chorioretinopathy (CSC).MethodsObservational, longitudinal, cross-sectional...
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Examining outcome expectancies for smoking vs. abstinence among adult daily smokersPublication date: March 2020Source: Addictive Behaviors, Volume 102Author(s): Amanda Kaufmann, Elizabeth J. Malloy, David A.F. HaagaAbstractIn a motivational interviewing (MI) framework of decision-making, we consider potential outcomes for both a primary choice and an alternative choice (DiClemente & Velazquez, 2002). Thus, we would expect that motivation to quit smoking is related to expectancies for quitting...
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The Hierarchy of Different Treatments for Arthrogenous Temporomandibular Disorders: A Network Meta-Analysis of Randomized Clinical TrialsPublication date: Available online 5 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Essam Ahmed Al-Moraissi, Larry M. Wolford, Edward Ellis, Andreas NeffAbstractPurposeDifferent treatment options for patients with arthrogenous Temporomandibular Disorders (TMDs) have been reported. However, evidence regarding the most effective intervention...
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Cross-Country Comparison of School Neighborhood Food Environments in Houston, Texas and Guadalajara, MexicoAbstractStudies in the U.S. and Mexico have observed the clustering of food resources around schools, which may promote the use of these resources. Our study characterized and compared school neighborhood food environments in Guadalajara, Jalisco, and Houston, Texas, and examined socioeconomic disparities in food resource availability across school neighborhoods. We used the Goods and Services...
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Vedolizumab Concentrations Are Associated with Long-Term Endoscopic Remission in Patients with Inflammatory Bowel DiseasesThe original version of the article unfortunately contained a couple of errors. In 'methods' section, in 'Outcomes' subsection, the sentence 'Endoscopic remission was defined as an SESCD ≤ 2 in patients with CD and an EMS ≤ 2 in UC patients while off corticosteroids.'Retraction Note: CD109 Mediates Cell Survival in Hepatocellular Carcinoma CellsThis article [1] is retracted at...
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Clinical Course and Management of Dengue in Children Admitted to Hospital: A 5 Years Prospective Cohort Study in Jakarta, IndonesiaBackground: Dengue incidence is rising globally which was estimated 100 million per year, whereas in Indonesia was estimated 7.5 million per year. Dengue clinical course varies from mild dengue fever (DF) to dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Patients, clinicians and care facilities would benefit if reliable predictors can determine at admission...
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Screening for Trisomies by cfDNA Testing of Maternal Blood in Twin Pregnancy: Update of the Fetal Medicine Foundation Results and Meta-analysis(Abstracted from Ultrasound Obstet Gynecol 2019;53:734–742) Cell-free DNA (cfDNA) analysis of maternal blood is useful and effective when screening for trisomies 21, 18, and 13 in singleton pregnancies. However, in twin pregnancies, data on cfDNA tests are much more limited: in a previous literature review and meta-analysis, there were only 5 prospective studies.Cerclage...
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Professional Educational OpportunitiesFrom the Editor of Sexuality and Disability : Global Perspectives on Sexuality and DisabilityCorrection to: Nursing Students' Experiences on Assessing the Sexuality of Patients: Mixed Method StudyThe original version of the article was published with incorrect tables. The correct version of the tables is presented in this erratum.Contraceptive Practices and Reproductive Health Considerations for Adolescent and Adult Women with Intellectual and Developmental Disabilities:...
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Komplexität, Komplizität und moralischer Stress in der PflegeZusammenfassungProfessionelles Handeln bedarf moralischen Handlungsvermögens. Im Kontext pflegerischer Weiterbildungen beschreibt der Philosoph Andrew Jameton vor über drei Jahrzehnten psychologische Reaktionen auf kompromittiertes moralisches Handlungsvermögen, die er als moralischen Stress definiert. Diese Standarddefinition hat in der Pflegewissenschaft zu einer dichten Forschung geführt und zum Vorschlag einer weiten Definition. Belegt...
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Disparities in surgery for early-stage cancer: the impact of refusalAbstractBackgroundFor early-stage cancer surgery is often curative, yet refusal of recommended surgical interventions may be contributing to disparities in patient treatment. This study aims to assess predictors of early-stage cancers surgery refusal, and the impact on survival.MethodsPatients recommended surgery with primary stage I and II lung, prostate, breast, and colon cancers, diagnosed between 2007–2014, were identified in...
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Evaluation of arsenic induced toxicity based on arsenic accumulation, translocation and its implications on physio-chemical changes and genomic instability in indica rice ( Oryza sativa L.) cultivarsAbstractArsenic (As) accumulation in rice is a principal route of As exposure for rice based population. We have tested physiochemical and molecular parameters together to identify low As accumulating rice cultivars with normal growth and vigor. The present study examined potential toxicity caused by...
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Biomolecules, Vol. 9, Pages 748: What Happened to the Phycobilisome? Biomolecules, Vol. 9, Pages 748: What Happened to the Phycobilisome? Biomolecules doi: 10.3390/biom9110748 Authors: Beverley R. Green The phycobilisome (PBS) is the major light-harvesting complex of photosynthesis in cyanobacteria, red algae, and glaucophyte algae. In spite of the fact that it is very well structured to absorb light and transfer it efficiently to photosynthetic reaction centers, it has been completely lost in the...
Tue Nov 19, 2019 10:36
Biomolecules, Vol. 9, Pages 748: What Happened to the Phycobilisome? Biomolecules, Vol. 9, Pages 748: What Happened to the Phycobilisome? Biomolecules doi: 10.3390/biom9110748 Authors: Beverley R. Green The phycobilisome (PBS) is the major light-harvesting complex of photosynthesis in cyanobacteria, red algae, and glaucophyte algae. In spite of the fact that it is very well structured to absorb light and transfer it efficiently to photosynthetic reaction centers, it has been completely lost in the...
Tue Nov 19, 2019 10:36
Biomolecules, Vol. 9, Pages 748: What Happened to the Phycobilisome? Biomolecules, Vol. 9, Pages 748: What Happened to the Phycobilisome? Biomolecules doi: 10.3390/biom9110748 Authors: Beverley R. Green The phycobilisome (PBS) is the major light-harvesting complex of photosynthesis in cyanobacteria, red algae, and glaucophyte algae. In spite of the fact that it is very well structured to absorb light and transfer it efficiently to photosynthetic reaction centers, it has been completely lost in the...
Tue Nov 19, 2019 10:36
Glial mitochondrial function and dysfunction in health and neurodegenerationPublication date: December 2019Source: Molecular and Cellular Neuroscience, Volume 101Author(s): Kevin McAvoy, Hibiki KawamataAbstractMitochondria play essential metabolic roles in neural cells. Mitochondrial dysfunction has profound effects on the brain. In primary mitochondrial diseases, mutations that impair specific oxidative phosphorylation (OXPHOS) proteins or OXPHOS assembly factors lead to isolated biochemical defects...
Tue Nov 19, 2019 10:05
Influence of PacC on the environmental stress adaptability and cell wall components of Ganoderma lucidumPublication date: January 2020Source: Microbiological Research, Volume 230Author(s): Yanru Hu, Lingdan Lian, Jiale Xia, Shishan Hu, Wenzhao Xu, Jing Zhu, Ang Ren, Liang Shi, Ming Wen ZhaoAbstractThe transcription factor PacC/Rim101 participates in environmental pH adaptation, development and secondary metabolism in many fungi, but whether PacC/Rim101 contributes to fungal adaptation to environmental...
Tue Nov 19, 2019 10:05
Comparison of adherence to ARRIVE guidelines in animal research articles published in the years 2009 and 2016 in pharmacology journals: An observational studySharmila Jalgaonkar, Tausif Mapara, Apoorv Verma, Mohsin SayyedJournal of Pharmacology and Pharmacotherapeutics 2019 10(3):77-84Objective: To evaluate and compare the adherence of the ARRIVE guidelines before and after its introduction by the articles published by two leading journals publishing animal research articles. Materials and Methods:...
Tue Nov 19, 2019 10:04
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