- National Update on Measles Cases and Outbreaks — United States, January 1–October 1, 2019 Manisha...National Update on Measles Cases and Outbreaks — United States, January 1–October 1, 2019Manisha Patel, MD; Adria D. Lee, MSPH; Nakia S. Clemmons, MPH; et al.During January–September 2019, 1,249 U.S. measles cases were reported, the highest annual number since 1992.MMWR Masthead15:41Left-versus-right-adrenal-volume ratio as a screening index before adrenal venous sampling to identify unilateral primary aldosteronism patientsObjectives: The current study aimed to investigate the value of the computed tomography-based left-versus-right adrenal gland volume ratio (L/Rv) in screening patients with unilateral primary aldosteronism. Methods: The current study recruited 114 patients who underwent successful adrenal venous sampling (AVS) and adrenal computed tomography at West China...15:40Veau III and Veau IV Cleft Palate: Do Peri-Operative Complications Differ?Objective: The Veau classification represents the most commonly used system for characterizing cleft palate severity. Conflicting evidence exists as to how increasing Veau classification affects outcomes. This study compared perioperative outcomes between Veau III and IV cleft palate repairs. Methods: The National Surgical Quality Improvement Program Pediatric (NSQIP-P) database was used to identify cleft palate repairs between...15:39Middle Ear Muscle Reflex and Word Recognition in "Normal-Hearing" Adults: Evidence for Cochlear Synaptopathy?Objectives: Permanent threshold elevation after noise exposure, ototoxic drugs, or aging is caused by loss of sensory cells; however, animal studies show that hair cell loss is often preceded by degeneration of synapses between sensory cells and auditory nerve fibers. The silencing of these neurons, especially those with high thresholds and low spontaneous rates, degrades auditory processing...15:37Burden of exposure to medical radiation following an acute coronary syndromeNo abstract availableEstimates of radiation exposure and subsequent risk of malignancy due to cardiac imaging in the emergency department for evaluation of chest pain: a cohort studyNo abstract availableTemporal pattern of neutrophil-to-lymphocyte ratio in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary interventionNo abstract availableDissociation of coronary computed tomography...15:37Impact of the microbiota on solid organ transplant rejectionPurpose of review The microbiota in mammalian hosts can affect maturation and function of the immune system and has been associated with health and disease. We will review new findings on how this dynamic environmental factor impacts alloimmunity and therapy in transplant hosts. Recent findings The microbiota changes after transplantation and immunosuppressive therapy. New data indicate that different microbial community structures have...15:36Precision medicine in severe pediatric asthma: opportunities and challengesPurpose of review Severe pediatric asthma exerts a substantial burden on patients, their families and society. This review provides an update on the latest insights and needs regarding the implementation of precision medicine in severe pediatric asthma. Recent findings Biologicals targeting underlying inflammatory pathways are increasingly available to treat children with severe asthma, holding the promise to enable precision...15:35Lipid management in people with peripheral artery diseasePurpose of review To summarize recent data on the role of dyslipidaemia and the benefit from managing this in people with disease of the abdominal aorta and its peripheral branches (peripheral artery disease, PAD). Recent findings Findings from the Further Cardiovascular Outcomes Research with Proprotein convertase subtilisin/kexin type 9 (PCSK9) Inhibition in Subjects with Elevated Risk (FOURIER) trial demonstrate the benefit of intensely...15:34The patient with severe traumatic brain injury: clinical decision-making: the first 60 min and beyondPurpose of review There is an urgent need to discuss the uncertainties and paradoxes in clinical decision-making after severe traumatic brain injury (s-TBI). This could improve transparency, reduce variability of practice and enhance shared decision-making with proxies. Recent findings Clinical decision-making on initiation, continuation and discontinuation of medical treatment may encompass substantial...15:33Flu Vaccination Recommendations for the 2019-2020 SeasonAlthough influenza seasons vary in severity, influenza can cause millions of illnesses, hundreds of thousands of hospitalizations, and tens of thousands of deaths worldwide each season. Dr. Lisa Grohskopf, a medical officer in CDC's Influenza Division, discusses the 2019-2020 influenza vaccine recommendations in a recently published CDC Medscape expert commentary.Learn MoreFight Flu this Season!CDC recommends a yearly flu vaccine as the first...15:32Ischemia-modified Albumin as a Biomarker for Prediction of Poor Outcome in Patients With Traumatic Brain Injury: An Observational Cohort StudyBackground: Biomarkers can assist in outcome prediction and therapeutic decision making after traumatic brain injury (TBI). The aim of this study was to evaluate the role of ischemia-modified albumin (IMA) in the prediction of mortality in patients with TBI. Methods: In this observational study IMA was measured on admission to intensive care unit (D0) and 24...15:31Human Kidney Immune Cell Map Reveals Multiple Infection Protection ZonesPublished on Sep 26, 2019Prometheus Biosciences, Takeda Pharmaceutical to Codevelop Targeted Therapies, CDx for IBDPublished on Oct 04, 2019Sample Normalization with Optimized Nucleic Acid ExtractionDownload this application note to learn about how RNAGEM's excellent yield linearity provides a superior approach to estimating total RNA quantity for sample normalization.Download it from GenomeWeb's White Paper Channel.15:30Whole-tumor histogram analysis of DWI and QSI for differentiating between meningioma and schwannoma: a pilot studyAbstractPurposeTo investigate whether whole-tumor histogram analyses of diffusivity measurements derived from q-space imaging (QSI) improves the differentiation between meningioma and schwannoma.Materials and methodsFifteen extra-axial tumors (11 meningiomas and 4 schwannomas) with MR examinations from April 2011 to May 2013 were included. Three-dimensional regions of interest (ROI) encompassed...15:30the RadioGraphics , Visit rsna.org/learning-center-rg today. Latest Articles Chest Imaging Immune...the RadioGraphics ,Visit rsna.org/learning-center-rg today. Latest ArticlesChest Imaging Immune Checkpoint Inhibitor Therapy–related Pneumonitis: Patterns and Management Immune checkpoint therapy–related pneumonitis is an uncommon but potentially serious complication with several distinct radiologic patterns that overlap with those of other infectious and inflammatory conditions. Kevin R. Kalisz, Nikhil H. Ramaiya...Amit GuptaGastrointestinal Imaging Chronic Pancreatitis or Pancreatic Tumor? A...15:29FDG PET/CT Image for a Rosai-Dorfman Disease With Pituitary and Bone Involvement in a Pediatric PatientRosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a rare nonneoplastic histiocytic disorder that often involves the lymph nodes and occasionally the central nervous system or skeleton. However, the presence of extranodal Rosai-Dorfman lesions without lymphadenopathy is extremely rare. Here we present a case of a pathological confirmed Rosai-Dorfman disease...15:29This illustration depicts a three-dimensional (3D), computer-generated image of a grouping of Giardia lamblia parasites. The artistic recreation was based upon scanning electron microscopic (SEM) imagery.More InfoCaptured at a Trianon, Haiti community spring source in February 2013, three years after a devastating earthquake, this image depicted two National Directorate for Drinking Water ...More >Entitled, "Hand-Drawn Map of Konduga LGA", this image was captured by CDC Microbiologist, Alford...15:28Loud Noises Damage Hearing,CDC supports "National Protect Your Hearing Month," and encourages people to use hearing protection (earplugs and noise-cancelling earmuffs) to protect their hearing from loud noises. Moreover, to get their hearing checked if they think there might be a problem with their hearing.Learn MoreBreast Cancer AwarenessOther than skin cancer, breast cancer is the most common cancer among American women. Mammograms are the best way to find breast cancer early, when it is easier...15:27The prospect of discovering new biomarkers for ovarian cancer based on current knowledge of susceptibility loci and genetic variation (Review)Mikael Kronborg Christophersen, Claus Høgdall, Estrid HøgdallView Abstract ❯Decreased collagen type III synthesis in skin fibroblasts is associated with parastomal hernia following colostomyFenglin Zhao, Fuqiang Chen, Xin Yuan, Yiting Liu, Jie ChenView Abstract ❯MicroRNA‑379‑5p suppresses renal fibrosis by regulating the LIN28/let‑7 axis in diabetic nephropathyNan...15:27Flow-Safe II+® Disposable BiLevel CPAP Device Available NowFlow-Safe II+ is the only available Disposable BiLevel CPAP system. Includes a manometer for verifying pressures. Easy set-up. Ideal for transport and where backup Bilevel equipment is unavailable.Learn moreFree Webinar on Capnography in EMS from MedtronicJoin us on Wednesday, Oct. 9 at 12 p.m. EST to learn about the principles of capnography and basic information about respiratory anatomy and physiology. Earn 1 CE credit for attending.Register...15:26Open Mastoid Cavity Obliteration With a High-Porosity Hydroxyapatite Ceramic Leads to High Rate of Revision Surgery and Insufficient Cavity ObliterationObjective: To assess long-term results and present experience with a high-porosity hydroxyapatite ceramic for obliterating large open mastoid cavities. Study-Design: Cross-sectional cohort study. Setting: Tertiary academic referral center. Patients: All patients who underwent tympanomastoid surgery for chronic middle ear disease or revision surgery...15:26Potential Liability for Physicians Using Artificial IntelligenceW. Nicholson Price II, JD, PhD; Sara Gerke, Dipl-Jur Univ; I. Glenn Cohen, JDJAMA CLINICAL GUIDELINES SYNOPSISPrimary Prevention of Cardiovascular DiseaseAtul Jain, MD, MS; Andrew M. Davis, MD, MPHTrending CME articles from JN Learning™Trends in Use of Medical Imaging in US Health Care Systems and in Ontario, Canada, 2000-2016 | CMEEffect of Combined Behavioral and Physical Therapy With Surgery vs Surgery Alone for Mixed Urinary Incontinence | CMETrends...15:25Shorter Height is Associated with Lower Probability of Liver Transplantation in Patients with Hepatocellular CarcinomaBackground: The effect of height and sex on liver transplantation (LT) for hepatocellular carcinoma (HCC) remains unclear. Methods: Using United Network for Organ Sharing (UNOS) data, 14,844 HCC patients listed for LT from 2005-2015 were identified. Cumulative incidence of waitlist events (LT and dropout for death or too sick) were calculated and modeled using Fine and Gray competing...15:24nRichDx Targets Liquid Biopsy Space With Magnetic Sample Prep PlatformPublished on Oct 04, 2019 Adding RNA-Seq, Ambry Genetics Expects to Reduce VUS Results in Hereditary Cancer TestsPublished on Oct 04, 2019 Canopy Biosciences Using Zellkraftwerk Buy to Move Into Protein AnalysisPublished on Oct 03, 2019 Blueprint Genetics to Open North American Lab as Biopharma Business GrowsPublished on Oct 03, 2019Your Digital Marketing PartnerGenomeWeb's advertising team can help you meet your online marketing...15:24Self-Limited Spinal Subarachnoid Hemorrhage After Lumbar Spinal Drain Removal While on Clopidogrel: A Case ReportSpinal subarachnoid hemorrhage (SSH) is a rare yet potentially devastating complication of neuraxial procedures. We present a case of SSH after inadvertent lumbar spinal drain removal while on clopidogrel. The contrast between the patient's mild clinical symptoms compared to his impressive magnetic resonance imaging (MRI) highlights the variable presentations that can be seen with spinal...15:24Ballistic and Penetrating Injuries of the ChestBallistic injuries are a major cause of morbidity and mortality in the United States. Unstable patients have high mortality, and only a small subset arrive at the hospital alive. Many patients undergo emergent surgery upon arrival, but a small subset undergo imaging with plain film, computed tomography, and echocardiography. We present a pictorial essay of ballistic and penetrating injuries and their complications with a focus on lung, cardiac, and vascular...15:23SAGE Publications Ltd STM: Chronic Respiratory Dis...The New England Journal of Medicine: Endocrinology...Clinical AnatomySuccess Rate in Puncture of the Te...Journal of Adolescent and Young Adult OncologySubc...RhinologyDevelopment of a new psychophysical metho...Journal of Neurological Surgery Part B: Skull Base...Pediatric RadiologyModification of chest radiograp...Clinical OtolaryngologyHealthcare utilization, fol...The Journal of PhysiologyCorticospinal excitabilit...JoVE: Journal of Visualized...Fri Oct 04, 2019 10:28Allergology InternationalRecent advances in eosinophil-related diseasesPublication date: October 2019Source: Allergology International, Volume 68, Issue 4Author(s): Hiroshi NakajimaAllergology InternationalFri Oct 04, 2019 05:58Upper respiratory tract infectionAge-related pathology associated with H1N1 A/California/07/2009 influenza virus infection.Related ArticlesAge-related pathology associated with H1N1 A/California/07/2009 influenza virus infection. Am J Pathol. 2019 Oct 01;: Authors: Bissel...16:07pubmed: future oncologyMolecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer.Related ArticlesMolecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer. Drug Resist Updat. 2019 Sep 17;46:100644 Authors: Leonetti A, Wever B, Mazzaschi G, Assaraf YG, Rolfo C, Quaini F, Tiseo M, Giovannetti E Abstract Immunotherapy has prompted a paradigm shift in advanced non-small cell lung...16:05Targeted Intervention to Increase Awareness of Opioid Overprescribing Significantly Reduces Narcotic Prescribing Within an Academic Orthopaedic PracticePublication date: Available online 4 October 2019Source: Journal of Surgical EducationAuthor(s): Connor King, John Curran, Shwetha Devanagondi, Tessa Balach, Megan Conti MicaObjectiveTo evaluate the impact of a targeted intervention focused on increasing awareness of opioid overprescribing within an academic orthopaedic practice.DesignRetrospective...16:04BMC Research NotesA new PacBio genome sequence of an Australian Pyrenophora tritici-repentis race 1 isolateThe necrotrophic fungal pathogen Pyrenophora tritici-repentis (Ptr) is the causal agent of tan spot a major disease of wheat. We have generated a new genome resource for an Australian Ptr race 1 isolate V1 to sup...BMC Research NotesThu Oct 03, 2019 17:00Malaria outbreak investigation in Tanquae Abergelle district, Tigray region of Ethiopia: a case–control studyWe investigated this outbreak...16:02PeerJ Computer ScienceDifferent expression pattern of flowering pathway genes contribute to male or female organ development during floral transition in the monoecious weed Ambrosia artemisiifolia L. (Asteraceae)The highly allergenic and invasive weed Ambrosia artemisiifolia L. is a monoecius plant with separated male and female flowers. The genetic regulation of floral morphogenesis is a less understood field in the reproduction biology of this species. Therefore the objective of this work was to...16:01Medical Image AnalysisSegmentation and Quantification of Infarction without Contrast Agents via Spatiotemporal Generative Adversarial LearningPublication date: Available online 4 October 2019Source: Medical Image AnalysisAuthor(s): Chenchu Xu, Joanne Howey, Pavlo Ohorodnyk, Mike Roth, Heye Zhang, Shuo LiAbstractAccurate and simultaneous segmentation and full quantification (all indices are required in a clinical assessment) of the myocardial infarction (MI) area are crucial for early diagnosis and...16:00MedgadgetComplex Hydrogel Structures to Host Living Cells Printed Using New TechniqueHydrogels are one of the hottest materials in biomedical research these days, as anyone following this publication will attest to. They're biocompatible, have the squishy consistency of soft tissues, and they can be tinkered with to host living cells, deliver drugs, and hopefully one day serve as replacements for diseased tissues and organs. Hydrogels' unique lightness and softness, though, makes it hard to 3D print...15:59ScienceDirect Publication: TalantaPET probe with Aggregation Induced Emission characteristics for the specific turn-on of aromatasePublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Renbo Wu, Song Liu, Yajing Liu, Yuli Sun, Hao Xiao, Yong Huang, Zequn Yang, Zehui WuAbstractAromatase is an attractive target for the diagnosis and treatment of breast cancer. To combine the anti-photobleaching properties of Aggregation Induced Emission (AIE) with the high sensitivity and whole-body...15:58Nutrients, Vol. 11, Pages 2377: The Effect of Coffee Consumption on the Prevalence of Diabetes Mellitus: The 2012–2016 Korea National Health and Nutrition Examination SurveyNutrients, Vol. 11, Pages 2377: The Effect of Coffee Consumption on the Prevalence of Diabetes Mellitus: The 2012–2016 Korea National Health and Nutrition Examination Survey Nutrients doi: 10.3390/nu11102377 Authors: Yejee Lim Youngmi Park Sun Kyu Choi Soyeon Ahn Jung Hun Ohn An inverse association between coffee consumption and...15:57Journal of Clinical MedicineJCM, Vol. 8, Pages 1633: Percutaneous Computed Tomography-Guided Coaxial Core Biopsy for the Diagnosis of Pancreatic TumorsJCM, Vol. 8, Pages 1633: Percutaneous Computed Tomography-Guided Coaxial Core Biopsy for the Diagnosis of Pancreatic Tumors Journal of Clinical Medicine doi: 10.3390/jcm8101633 Authors: Su Liu Chao Chiang Yen Tsai Endoscopic, ultrasound-guided tissue acquisition (EUS-TA) with rapid on-site evaluation is recommended as a first choice in the diagnosis...15:56Antibiotics, Vol. 8, Pages 176: The Preoperative Inflammatory Status Affects the Clinical Outcome...Antibiotics, Vol. 8, Pages 176: The Preoperative Inflammatory Status Affects the Clinical Outcome in Cardiac SurgeryAntibiotics, Vol. 8, Pages 176: The Preoperative Inflammatory Status Affects the Clinical Outcome in Cardiac Surgery Antibiotics doi: 10.3390/antibiotics8040176 Authors: D'Agostino Cappabianca Rotunno Castellaneta Quagliara Carrozzo Mastro Charitos Beghi Aims: There are many reasons for the increase in post-operative mortality and morbidity in patients undergoing surgery. In fact, an...15:55Diiodothyronines regulate metabolic homeostasis in primary human hepatocytes by modulating mTORC1...Diiodothyronines regulate metabolic homeostasis in primary human hepatocytes by modulating mTORC1 and mTORC2 activity.Related ArticlesDiiodothyronines regulate metabolic homeostasis in primary human hepatocytes by modulating mTORC1 and mTORC2 activity. Mol Cell Endocrinol. 2019 Sep 30;:110604 Authors: Gnocchi D, Ellis ECS, Johansson H, Eriksson M, Bruscalupi G, Steffensen KR, Parini P Abstract Until three decades, ago 3,5-diiodothyronine (3,5-T2) and 3,3'-diiodothyronine (3,3'-T2) were considered...15:54American Journal of Clinical Oncology - Published Ahead-of-PrintDefinitive Radiation Treatment Patterns and Outcomes for Low and Intermediate Risk Prostate Cancer Patients: A Cross-Continental Comparative StudyPurpose: To evaluate early-stage prostate cancer (PCa) radiotherapy treatment patterns and outcomes among Ghanaian men (GM) compared with US men (USM). Materials and Methods: This retrospective study consists of 987 National Comprehensive Cancer Network low risk, favorable intermediate risk,...15:52Gait & PostureLower Extremity Characteristics in Recurrent Clubfoot: Clinical and Gait Analysis Findings that may Influence Decisions for Additional SurgeryPublication date: Available online 4 October 2019Source: Gait & PostureAuthor(s): Kristan A. Pierz, Jessica R. Lloyd, Matthew J. Solomito, Phil Mack, Sylvia ÕunpuuGait & Posture12:59Ground reaction force adaptation during cross-slope walking on railroad ballastPublication date: Available online 4 October 2019Source: Gait & PostureAuthor(s):...15:52Auris Nasus LarynxA summary of the Clinical Practice Guideline for the Diagnosis and Management of Voice Disorders, 2018 in JapanPublication date: Available online 4 October 2019Source: Auris Nasus LarynxAuthor(s): Hirohito Umeno, Masamitsu Hyodo, Tomoyuki Haji, Hirotaka Hara, Mitsuyoshi Imaizumi, Miyoko Ishige, Masanobu Kumada, Kiyoshi Makiyama, Noriko Nishizawa, Koichiro Saito, Osamu Shiromoto, Atsushi Suehiro, Goro Takahashi, Ichiro Tateya, Koichi Tsunoda, Koichi OmoriAbstractObjectiveTo develop...15:51Clinical Neurology and NeurosurgeryIncreasing the diagnostic yield of stereotactic brain biopsy using intraoperative histological smearPublication date: Available online 3 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Bertrand Mathon, Aymeric Amelot, Karima Mokhtari, Franck BielleAbstractObjectiveThe negative biopsy rate approaches 5% in the literature. In our institution, this rate was 2.6% (42/1638) over a ten-year period (2007-2016). We aimed to assess the diagnostic yield...15:51Anti-Cancer Drugs - Published Ahead-of-Print Efficacy of gefitinib at reduced dose in EGFR mutant...Anti-Cancer Drugs - Published Ahead-of-PrintEfficacy of gefitinib at reduced dose in EGFR mutant non-small cell lung carcinomaAs a first-generation epidermal growth factor receptor-tyrosine kinase inhibitor, gefitinib was approved by the US Food and Drug Administration for treatment of advanced non-small cell carcinoma with sensitizing EGFR mutations. Gefitinib is known to have adverse effects, which may necessitate dose reduction or even change to alternative preparation of epidermal growth factor...15:50Pediatric ganglioglioma of the brainstem and cervicomedullary junction: a retrospective cohort study.Related ArticlesPediatric ganglioglioma of the brainstem and cervicomedullary junction: a retrospective cohort study. J Neurosurg Pediatr. 2019 Oct 04;:1-7 Authors: Oushy S, Perry A, Graffeo CS, Raghunathan A, Carlstrom LP, Daniels DJ Abstract OBJECTIVE: Ganglioglioma is a low-grade central nervous system neoplasm with a pediatric predominance, accounting for 10% of all brain tumors in children. Gangliogliomas...15:50Biomarkers in the risk assessment for stroke and dementia in atrial fibrillationPurpose of review Atrial fibrillation is one of the most common clinically encountered arrhythmias exhibiting a strong association with a spectrum of cerebral injuries from the occurrence of clinical stroke, subclinical stroke, dementia, and cognitive decline. Dynamic noninvasive specific and sensitive diagnostic tests may allow a personalized approach to the atrial fibrillation patient's treatment based upon quantitative...15:49Precision medicine in atopic diseasesPurpose of review To analyze the status of precision medicine in atopic diseases. Recent findings Atopic diseases are increasingly recognized as heterogeneous in nature and they can be quite different in severity, response to therapy, triggers, genetic back ground, ancestral risk and type of inflammation. This significant variability in the landscape of atopic diseases is not reflected in the common treatment guidelines that follow 'one fits all' approach for...15:49Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain: A Randomized Controlled StudyObjectives: Despite the interest in scientific community, there is still poor evidence about pulsed radiofrequency efficacy in the treatment of neuropathic pain. In order to determine if high-voltage pulsed radiofrequency plus adhesiolysis (PRF-EA) showed better results than epidural adhesiolysis alone (EA), a randomized, double-blind,...15:48Cell Cycle Biomarkers and Soluble Urokinase-Type Plasminogen Activator Receptor for the Prediction of Sepsis-Induced Acute Kidney Injury Requiring Renal Replacement Therapy: A Prospective, Exploratory StudyObjectives: Sepsis-induced acute kidney injury is the dominant acute kidney injury etiology in critically ill patients and is often associated with a need for renal replacement therapy. The indication and timing of renal replacement therapy are controversially discussed. We hypothesized that the...15:48Validation of the YuWell YE680B upper-arm blood pressure monitor in adults according to the ANSI/AAMI/ISO 81060-2: 2013 standardObjective: To evaluate the accuracy of the YuWell YE680B oscillometric upper-arm blood pressure monitor for clinic and home blood pressure measurements in adults according to the American National Standards Institute/the Association for the Advancement of Medical Instrumentation/International Organization for Standardization (ANSI/AAMI/ISO) 81060-2:2013 standard. Method:...15:47The roles of fission yeast exonuclease 5 in nuclear and mitochondrial genome stabilityPublication date: November 2019Source: DNA Repair, Volume 83Author(s): Justin L. Sparks, Kimberly J. Gerik, Carrie M. Stith, Bonita L. Yoder, Peter M. BurgersAbstractThe Exo5 family consists of bi-directional, single-stranded DNA-specific exonucleases that contain an iron-sulfur cluster as a structural motif and have multiple roles in DNA metabolism. S. cerevisiae Exo5 is essential for mitochondrial genome maintenance,...15:47Clinical Tests of the Shoulder: Accuracy and Extension Using Dynamic UltrasoundShoulder pain is a common musculoskeletal disorder that has a significant impact on the patient's quality of life and functional health. Since the shoulder joint is a complex structure, the relevant symptoms of shoulder pain may not directly reflect the underlying pathology. Hence, several shoulder tests have been developed to examine shoulder problems, and their diagnostic accuracy varies. Familiarization with the performance...15:47Co-morbidities of HIV infection: role of Nef-induced impairment of cholesterol metabolism and lipid raft functionalityCombination anti-retroviral therapy (cART) has dramatically changed the outcome of HIV infection, turning it from a death sentence to a manageable chronic disease. However, co-morbidities accompanying HIV infection, such as metabolic and cardio-vascular diseases, as well as cognitive impairment, persist despite successful virus control by cART and pose considerable challenges to clinical...15:46L'évolution des normes face au développement des objets de santé connectésPublication date: October 2019Source: Médecine & Droit, Volume 2019, Issue 158Author(s): Valérie Siranyan, Olivier ToucasRésuméLes offres d'applications mobiles et d'objets connectés se multiplient sur internet, dans les magasins de vente de matériel médical mais aussi dans le réseau de la grande distribution. Ces produits de santé ou de bien-être n'ont cependant pas tous, un statut juridique bien déterminé, garant de la...15:46Transungual Excision of Glomus Tumors: A Treatment and Quality of Life StudyBACKGROUND Glomus tumors are rare benign painful tumors, frequently found in the subungual region. Complete surgical excision is essential for relief of symptoms. The main postoperative complications are tumor recurrence and nail dystrophy. OBJECTIVE To evaluate the long-term outcome and the impact on quality of life (QoL) of glomus tumors after a transungual approach. MATERIALS AND METHODS A retrospective cohort study was...15:45Atteintes cutanée et oculaire révélatrices d'un lymphome T/NK extra-nodal de type nasalPublication date: October 2019Source: Annales de Dermatologie et de Vénéréologie, Volume 146, Issue 10Author(s): A. Marzouki-Zerouali, L. Charbit, M. Mitcov, F. Violon, J.-L. Schmutz, S. Moawad, A.-C. BursztejnRésuméIntroductionLe lymphome T/NK (Natural Killer) extra-nodal (LTNKEN) fait partie des lymphomes non hodgkiniens de haut grade de malignité. Il en existe deux types : les formes nasales avec atteinte primitive...15:45Cosmetic ScienceVolume 41, Issue 5Pages: i-iv, 411-515October 2019Issue InformationIssue InformationPages: i-iv | First Published: 03 October 2019Review Article Open AccessFacial skin mapping: from single point bio‐instrumental evaluation to continuous visualization of skin hydration, barrier function, skin surface pH, and sebum in different ethnic skin typesR. Voegeli, J. Gierschendorf, B. Summers, A. V. RawlingsPages: 411-424 | First Published: 20 July 2019 The skin mapping technology enables the...15:44Cosmetic DermatologyVolume 18, Issue 5Pages: 1171-1586October 2019ISSUE INFORMATIONIssue Information ‐ TOCPages: 1171-1173 | First Published: 03 October 2019CAAM ADVERTCAAM AdvertPages: 1178 | First Published: 03 October 2019EDITORIALJCD October 2019–Editor's letterMichael H. Gold MDPages: 1181 | First Published: 03 October 2019REVIEW ARTICLESAesthetic evolution drives birth of minimally invasive surgery subgroupSteve Dayan MDPages: 1182-1185 | First Published: 26 June 2019Nonvascular uses of pulsed...15:431.Head and Neck SupportGerman National Library of Science and Technology (TIB)WILKINS DONALD F; DOWNS JOSHUA LEE; BERZINS RONALD H2018-01-01 European Patent OfficeExample implementations relate to providing head and neck support. An example system includes a helmet, a load bearing harness, and a2.Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass.Science.gov (United States)van Harten AM; Poell JB; Buijze M; Brink A;...15:42Otorrinolaringología | Octubre 4, Nº 229Producido por la Sociedad Iberoamericana de Información Científica (SIIC)ARTÍCULOS DE FUENTES SELECCIONADASLos artículos de fuentes seleccionadas son resumidos en castellano por el Comité de Redacción Científica de SIIC.Elena Sánchez-LegazaPLASMOCITOMA EXTRAMEDULAR NASOFARÍNGEO: INFORME DE UN CASOEl plasmocitoma extramedular de nasofaringe es una neoplasia de células plasmáticas inusual, que comprende un 4% de las neoplasias no epiteliales a este nivel. Aparece...15:23Medicina Interna | Octubre 4, Nº 942Producido por la Sociedad Iberoamericana de Información Científica (SIIC)ARTÍCULOS DE FUENTES SELECCIONADASLos artículos de fuentes seleccionadas son resumidos en castellano por el Comité de Redacción Científica de SIIC.Renato CozziTRATAMIENTO COMBINADO CON DROGAS DOPAMINERGICAS Y SOMATOSTATINERGICAS EN PACIENTES CON ACROMEGALIAEn los pacientes con acromegalia, la normalización de los niveles de hormona de crecimiento y de factor de crecimiento tipo I similar a...15:22Advances in the diagnosis of giant cell arteritisPurpose of review To summarize recent advances in the diagnosis of giant cell arteritis (GCA). Recent findings Less common manifestations of GCA include corneal edema, proptosis from lacrimal gland ischemia and sensorineuronal hearing loss. Histology studies have suggested that temporal artery biopsies (TAB) with fixed specimen lengths of 15 mm may be adequate to prevent false negative biopsies. In centers with appropriate radiologic expertise, a European...15:22Nutrition Science to Take Center Stage in SeattleNo abstract availableNUTRITION GazetteNo abstract availableNEWSbreaksNo abstract availableNutritionist Guide to Direct-to-Consumer Genetic Tests and Precision NutritionAnalogous to precision medicine, precision nutrition aims to tailor nutritional recommendations based on personal needs to optimize health. The field of nutritional genomics, which refers to the bidirectional interplay between dietary nutrients and the genome, is providing some of the...15:21Current state of nonengrafting donor leukocyte infusion (focus on microtransplantation for acute myeloid leukemia)Purpose of review Microtransplantation (or micro-stem cell transplantation, MST) is one permutation of alloreactive immunotherapy increasingly studied in clinical trials. It is most commonly applied to patients with myeloid malignancies who are not suitable candidates for allogeneic hematopoietic cell transplantation. This review highlights the past 2 years of work on stem/progenitor...15:21Variation Between and Within Hospitals in Single Injection Caudal Local Anesthetic Dose: A Report From the Pediatric Regional Anesthesia NetworkBACKGROUND: Given that variation exists in health care utilization, expenditure, and medical practice, there is a paucity of data on variation within the practice of anesthesia. The Pediatric Regional Anesthesia Network (PRAN) data lend itself to explore whether different medical practice patterns exist and if there are nerve blocks with more local anesthetic...15:20Do We Have Evidence for Dietary and Nutritional Interventions for Autism Spectrum Disorder?Amy S. Weitlauf, Rachel H. Goode and Zachary WarrenReview ArticleDietary Interventions for Autism Spectrum Disorder: A Meta-analysisDavid Fraguas, Covadonga M. Díaz-Caneja, Laura Pina-Camacho, Carmen Moreno, Manuel Durán-Cutilla, Miriam Ayora, Emiliano González-Vioque, Mario de Matteis, Robert L. Hendren, Celso Arango and Mara Parellada15:20Dysregulation of glutaminase and glutamine synthetase in cancerPublication date: 28 December 2019Source: Cancer Letters, Volume 467Author(s): José M. Matés, José A. Campos-Sandoval, Juan de los Santos-Jiménez, Javier MárquezAbstractBesides fast glucose catabolism, many types of cancers are characterized by elevated glutamine consumption. Medical oncology pursuits to block specific pathways, mainly glycolysis and glutaminolysis, in tumor cells to arrest cancer development. This strategy frequently...15:19Pollicisation dans la prise en charge des hypoplasies et aplasies congénitales du pouce, résultats fonctionnels, à propos de 13 casPublication date: Available online 30 September 2019Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): P. Curings, D. Adam, C. Le Lardic, P. Perrot, A. Hamel, F. DuteilleRésuméIntroductionLa pollicisation de l'index, comme traitement de l'aplasie et de l'hypoplasie sévère congénitale du pouce reste une intervention exigeante sur le plan technique. Elle est généralement...15:18Put an End to Missed OpportunitiesThe ongoing transformation of America's health care system is bringing disruption in every sector of our industry. Hospital case management programs are similarly undergoing dramatic changes as care coordination for our most vulnerable patients becomes the focus of many hospital case management programs. As a result, case management leaders and human resource directors are disrupting legacy assumptions and expanding eligibility for the role of the hospital case manager.The...15:18Managing Immunosuppressed Patients With Inflammatory Bowel Disease During a Measles OutbreakNo abstract availableEndoscopic Management of Duodenal ObstructionNo abstract availablePneumomediastinum and Subcutaneous Emphysema Secondary to PolypectomyNo abstract availableCholangiopathy Associated With SyphilisNo abstract availableTranspapillary Endoscopic Removal of Gallbladder Stones Through a Fully Covered Metallic StentNo abstract availableContinuing Medical Education Questions: October 2019Article...15:17CI Candidacy: Disparity, Access Among Medicare BeneficiariesNo abstract availableSex Differences in Sound ProcessingNo abstract availableGenetic Susceptibility to Hearing Loss from Noise ExposureNo abstract availableClinical Advancements for Managing Hyperacusis with PainNo abstract availableBy the Numbers: Medicare and Cochlear Implant CoverageNo abstract availableCI for SSD: Translating New Indications into Better Patient OutcomesNo abstract availableEconomics of Cochlear Implant UtilizationNo...15:17Making a Correct Diagnosis of Glaucoma: Data From the EMGTPrécis: A correct diagnosis of glaucoma established at initial visits. Purpose: It has been suggested that a diagnosis of glaucoma cannot be certain until progression has been demonstrated. Our aim was to evaluate the correctness of a glaucoma diagnosis established after 2 initial visits. Patients and Methods: Patients included in the Early Manifest Glaucoma Trial (EMGT) who had continued follow-up for at least 15 years were included in this...15:16Treatment of Patients With Advanced Chronic Myeloid LeukemiaSimoneaux, RichardOncology Times. 41(19):1,5-6, October 5, 2019.FavoritesPDF Get Content & PermissionsFREECMS Proposes Simplified Payment Plan for Cancer Radiotherapy ServicesSamson, KurtOncology Times. 41(19):1,4, October 5, 2019.FavoritesPDF Get Content & PermissionsFREEExploring the CLL/Lymphoma Microenvironment to Improve TherapiesNeff Newitt, ValerieOncology Times. 41(19):1,9-10, October 5, 2019.FavoritesPDF Get Content &...15:16The European Hematology Exam: The Next Step toward the Harmonization of Hematology Training in EuropeNo abstract availableChildren and Adolescents with Chronic Myeloproliferative Neoplasms: Still an Unmet Biological and Clinical Need?No abstract availableIntroducing the HemaSphere Controversies SeriesNo abstract availableVon Willebrand Disease: From In Vivo to In Vitro Disease ModelsVon Willebrand factor (VWF) plays an essential role in primary hemostasis and is exclusively synthesized and stored...15:15Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents*Objectives: The epidemiology of clinically relevant bleeding in critically ill adolescents, particularly those who are at high risk of venous thromboembolism, is unclear. In preparation for a randomized clinical trial of pharmacologic prophylaxis against venous thromboembolism, we characterized the epidemiology of clinically relevant bleeding in critically ill adolescents. Design: Post hoc analysis of data from a pediatric...15:15Recovery of malnutrition in a patient with severe brain injury outcomes: A case reportRationale: Severe brain injury often induces a state of malnutrition due to insufficient caloric and protein input. If left untreated, it will have a negative impact on rehabilitation. Nutritional therapy provides caloric and the nutritional support necessary to cover the daily needs and help contrast hospital infections. Our hypothesis is that integration of natural foods in the daily diet can enhance the recovery...15:14Hypoxia with 18F-fluoroerythronitroimidazole integrated positron emission tomography and computed tomography (18F-FETNIM PET/CT) in locoregionally advanced head and neck cancer: Hypoxia changes during chemoradiotherapy and impact on clinical outcomeHypoxia is a well-recognized biological characteristic to therapy resistance and negative prognostic factor in patients with head and neck squamous cell carcinoma (HNSCC). This study aims to investigate the changes of hypoxia measured by 18F-fluoroerythronitroimidazole...15:14Peripheral osteoma of the nasal bone after laser treatment: A case reportIntroduction: Peripheral osteoma, which arises from the periosteum, commonly develops in the head and neck region and is found frequently in the mandible, maxilla, and paranasal sinuses. However, osteoma of the face, especially from the nasal bone, is quite rare. Patient concerns: A 34-year-old female visited our outpatient department with a small mass on the nose. She had n laser treatment of nevus at the same spot 14 years...15:13Effect of Uric Acid Control on Serum CreatinineObjective Hyperuricemia has been epidemiologically associated with multiple comorbidities including chronic renal failure and cardiovascular disease. Cause and effect are difficult to address, given comorbidities associated with and prevalence of metabolic syndrome. One impediment to achieving serum uric acid (sUa) levels less than or equal to 6.0 mg/DL is the concept that allopurinol might be nephrotoxic. We examined the relation of sUa less than or...15:12Allergology InternationalRecent advances in eosino...Pigment Cell & Melanoma Research,Volume 32, Issue 6Pages: i, 739-865November 2019COVER IMAGECover ImagePages: i | First Published: 04 October 2019 Excimer laser‐irradiated nevus depigmentosusISSUE INFORMATIONIssue InformationPages: 739-743 | First Published: 04 October 2019REVIEWNeuroblastoma rat sarcoma mutated melanoma: That's what we got so farElisa Bertoli, Marco Giavarra, Maria Grazia Vitale, Alessandro Marco MinisiniPages: 744-752 | First Published: 12 August 2019ORIGINAL ARTICLESThe TYRP1‐mediated...15:09
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Σάββατο 5 Οκτωβρίου 2019
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
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heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
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