Electroencephalogram Dynamics during General Anesthesia Predict the Later Incidence and Duration of Burst-suppression During Cardiopulmonary Bypass

Electroencephalogram (EEG) burst-suppression consists of quasi-periodic alternations between isoelectricity and brief bursts of electrical activity such as spikes, sharp waves, or slow waves (Young, 2000, Akeju et al., 2017). It reflects a brain state of relative cortical quiescence that is not observed during normal behavioral states of wake or sleep(Young, 2000, Brown et al., 2010, Akeju et al., 2017). Instead, it is closely associated with cortical pathologies such as diffuse anoxic brain injury, hypothermia and Ohtahara syndrome(Young, 2000, Brown et al., 2010, Akeju et al., 2017).

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