Impact of preoperative biopsy on severe submucosal fibrosis on endoscopic submucosal dissection for colorectal laterally spreading tumors: a propensity score analysis

It is thought that preoperative biopsy for superficial-type colorectal tumors should be avoided because submucosal fibrosis caused by biopsy makes endoscopic mucosal resection impossible. However, few studies have reported the influence of biopsy on colorectal endoscopic submucosal dissection (ESD). This study aimed to examine the effect of biopsy on submucosal fibrosis and treatment outcomes of ESD for laterally spreading tumors (LSTs).

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