Metidji et al. show that deletion of Ahr in intestinal epithelial cells results in a defective barrier and unrestricted proliferation of intestinal stem cells (ISCs), culminating in malignant transformation. Activation of AHR by dietary ligands guards the ISC niche and maintains intestinal barrier homeostasis.
https://ift.tt/2MeG4u5
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
▼
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
-
▼
Αυγούστου
(5863)
-
▼
Αυγ 14
(354)
- Emerging EZH2 Inhibitors and Their Application in ...
- Confidence Analysis of DEER Data and its Structura...
- Lipid-mediated interactions between the antimicrob...
- Effect of cytoskeleton elasticity on amoeboid swim...
- A luminal loop of Wilson disease protein binds cop...
- Biomembrane Adhesion to Substrates Topographically...
- Charge interactions can dominate coupled folding a...
- Co-entangled actin-microtubule composites exhibit ...
- Nonlinear elasticity of the ECM fibers facilitates...
- Immunophenotypic and cytogenetic evolution pattern...
- Toward a sensible single antigen bead cut-off base...
- Targeted Therapies for Brain Tumors: Will They Eve...
- Renin-Angiotensin System Inhibitors to Mitigate Ca...
- Development and Validation of a Prostate Cancer Ge...
- Adjuvant Therapy for Colon Cancer: Genes, Genes......
- Fratricide of NK Cells in Daratumumab Therapy for ...
- Cross-talk between T Cells and Hematopoietic Stem ...
- T-cell Dysfunction in Glioblastoma: Applying a New...
- Highlights of This Issue
- Integrative Kinome Profiling Identifies mTORC1/2 I...
- Curation of the Pancreatic Ductal Adenocarcinoma S...
- Aberrant Lck Signal via CD28 Costimulation Augment...
- Phase 0 Trial of AZD1775 in First-Recurrence Gliob...
- Metformin Targets Mitochondrial Glycerophosphate D...
- Andecaliximab/GS-5745 Alone and Combined with mFOL...
- Identification and Validation of Radiographic Enha...
- Phase IB/II Study of Second-Line Therapy with Pani...
- {Delta}Np63{gamma}/SRC/Slug Signaling Axis Promote...
- Cytokines Produced by Dendritic Cells Administered...
- Combined HDAC and Bromodomain Protein Inhibition R...
- Interferon Gamma Messenger RNA Signature in Tumor ...
- Adherence to anti-vectorial prevention measures am...
- Psychological features of abstinent heroin users b...
- Dengue fever manifesting with tetany as the first ...
- Gender of children and social provisions as predic...
- Highlights from Recent Cancer Literature
- Kras and Tp53 Mutations Cause Cholangiocyte- and H...
- Neoadjuvant-Intensive Androgen Deprivation Therapy...
- Recurrent RARB Translocations in Acute Promyelocyt...
- Epithelial-Mesenchymal Transition in Human Prostat...
- Aberrant FGFR Tyrosine Kinase Signaling Enhances t...
- Combined MR Imaging of Oxygen Consumption and Supp...
- PDSS2 Deficiency Induces Hepatocarcinogenesis by D...
- Tipifarnib Inhibits HRAS-Driven Dedifferentiated T...
- Enhanced Glycolysis Supports Cell Survival in EGFR...
- CRISPR/Cas9-Mediated Knockout of DGK Improves Anti...
- R-spondin3 Is Associated with Basal-Progenitor Beh...
- CD271+ Cells Are Diagnostic and Prognostic and Exh...
- DDX3 Activates CBC-eIF3-Mediated Translation of uO...
- Influence of Smoking, Body Mass Index, and Other F...
- Expression of Long Noncoding RNA YIYA Promotes Gly...
- From the Desk of the Editor
- Corylin inhibits LPS-induced inflammatory response...
- Editorial Board
- Table of Contents
- Methylomic analysis of ovarian cancers identifies ...
- Biochemical and Epigenetic Insights into L-2-Hydro...
- A clinical and molecular Phase II trial of oral EN...
- Kub5-Hera RPRD1B deficiency promotes "BRCAness" an...
- KMT2C mutations in diffuse type gastric adenocarci...
- Validation of miR-31-3p Expression to Predict Cetu...
- Most Postmenopausal Bleeding Not Associated With C...
- TBI Linked to Increased Suicide Risk
- Triple Combo Blood Pressure Pill Can Improve BP Co...
- AMA Adopts New Policy on Housing for Homeless
- Zika, West Nile Cases Reported in Alabama
- Rab GTPases in Osteoclastic Endomembrane Systems
- Gut Microbiome in BALB/c and C57BL/6J Mice Undergo...
- Epidemiology of measles in the metropolitan settin...
- Rapid and sensitive detection of Yersinia pestis b...
- C-reactive protein and procalcitonin to discrimina...
- Helcococcus ovis in a patient with an artificial e...
- Myalgia caused by chronic myositis associated with...
- CIDP, myasthenia gravis, and membranous glomerulon...
- Clinical Impact of Post-Progression Survival on Ov...
- Primary peritoneal Epithelioid mesothelioma of cle...
- Cancer mortality and incidence following external ...
- The growing importance of radiation worker studies
- Persistent inequalities in unplanned hospitalisati...
- Driver mutations of young lung adenocarcinoma pati...
- CIC‐NUTM1 fusion: A case which expands the spectru...
- A case of pediatric acute myeloid leukemia with t(...
- Secondary Neutron Dose from a Dynamic Collimation ...
- FDG / PET-CT based lymph node atlas in breast canc...
- Knowledge-based planning for identifying high-risk...
- NephroTalk: Evaluation of a Palliative Care Commun...
- Circulating Tumor Cells Dynamics in Pancreatic Ade...
- Validity of the Novel Taiwan Lymphoscintigraphy St...
- In the Next Issue
- Ensuring Equity, Diversity, and Inclusion in Acade...
- Long-term Quality of Life in Neonatal Surgical Dis...
- Decreased Risk of Delirium With Use of Regional An...
- Per-oral Pyloromyotomy (POP) for Medically Refract...
- Does Surgical Margin Impact Recurrence in Noninvas...
- Reduced Postburn Hypertrophic Scarring and Improve...
- IdeS (Imlifidase): A Novel Agent That Cleaves Huma...
- A Structured Compensation Plan Improves But Does N...
- Hyperthyroidism is Underdiagnosed and Undertreated...
- Timing of Carotid Endarterectomy After Stroke: Ret...
- An Academic Relative Value Unit System for Incenti...
-
▼
Αυγ 14
(354)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Τρίτη 14 Αυγούστου 2018
The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
This protocol presents an in vitro live-imaging phagocytosis assay to measure the phagocytic capacity of astrocytes. Purified rat astrocyt...
-
Association française pour l'étude du cancer [Imatinib in the treatment of chronic myeloid leukemia in Morocco]. Related Articles [Im...
-
A Case of Miller Fisher Syndrome Due to the Use of Cemiplimab : No abstract available Miller Fisher syndrome is a rare, acquired n...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.