Single cell RNA sequencing: a new window into cell scale dynamics

Single cell genomics has recently emerged as a powerful tool for observing multicellular systems at a much higher level of resolution and depth than previously possible. High throughput single cell RNA sequencing techniques are able to simultaneously quantify expression levels of several thousands of genes within individual cells for tens of thousands of cells within a complex tissue. This has led to development of novel computational methods to analyze this high dimensional data, investigating longstanding and fundamental questions regarding the granularity of cell types, the definition of cell states and transitions from one cell type to another along developmental trajectories.

https://ift.tt/2ugZV15