=Osteoradionecrosis of the Skull Base in Nasopharyngeal Carcinoma: Incidence and Risk Factors

Skull base ORN has been seldom reported, and it can be difficult to distinguish and easy to misdiagnose. In this study, we demonstrated the incidence of the skull base osteoradionecrosis(ORN) after one course of external beam radiotherapy (EBRT) in NPC patients. Complete medical records were reviewed; meanwhile, Magnetic Resonance Imaging (MRI) and nasopharyngeal endoscopy were performed during follow-up period after treatment. We analyzed the associated factors in an attempt to decrease the occurrence of ORN, promote the understanding of this condition and improve the quality of life in patients with ORN.

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