Multi-component intrinsic brain activities as a safe, alternative to cortical stimulation for sensori-motor mapping in neurosurgery

Functional brain mapping for the precise identification of the primary sensori-motor area (S1-M1) prior to epilepsy surgery is key for reducing the risk of postoperative functional deficits. This particular functional brain map was traditionally introduced by several methodologies, such as functional magnetic resonance imaging (fMRI) (Chakraborty et al., 2008), somatosensory evoked potentials (Dinner et al., 1986), and electrical cortical stimulation (ECS) (Ojemann et al., 1989, Awad et al., 1991, Branco et al., 2003).

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