Frontal EEG asymmetry in extremely low birth weight adult survivors: Links to antenatal corticosteroid exposure and psychopathology

The brain is particularly vulnerable to adverse environmental exposures during sensitive periods of development (Gluckman et al., 2008; Schlotz and Phillips, 2009). Infants born at extremely low birth weight (ELBW, <1000g) are exposed to significant perinatal adversity and provide a model that allows researchers to examine the impact of early life stress on neurodevelopment across the lifespan. While advances in neonatal care have significantly increased the number of ELBW infants surviving into adulthood (Stoll et al., 2015), relatively little is known about the long-term effects of preterm birth on the brain.

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