MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset

Intravenous thrombolysis with alteplase, a recombinant tissue plasminogen activator, is the standard medical treatment for acute ischemic stroke within 4.5 hours after the onset of symptoms. In 14 to 27% of strokes, the time of symptom onset is not known, frequently because stroke symptoms are…

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