Immunoassay helps limit overdiagnosis of Clostridium difficile infection

The recently published study by Brumbaugh et al1 summarized their retrospective experience with intragastric fecal microbiota transplantation (FMT) for recurrent Clostridium difficile infection (CDI) in 42 children (47 FMTs). The authors noted a much lower response rate of FMT in children with inflammatory bowel disease (IBD), 54% (7/13), compared with 94% (16//17) success in otherwise-healthy children.

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