EUS-FNA giving way to fine-needle biopsy: Is it time to retire your old trusted needles?

EUS-guided tissue acquisition (EUS-TA) plays a fundamental role in the diagnosis of pancreatic masses. The ideal EUS-TA technique and device is that which will maximize diagnostic yield, specimen adequacy, and accuracy while minimizing adverse event rates and costs.1 Several factors have an impact on EUS-TA outcomes, including (1) sampling methods and techniques (use of suction, fanning, capillary technique, number of passes, methods of sample expression), (2) availability of rapid onsite evaluation (ROSE), (3) endosonographer and cytopathologist qualifications (training and experience), and (4) type of specimen and needle used.

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