Tissue Engineering: Silicon Carbide Nanoparticles as an Effective Bioadhesive to Bond Collagen Containing Composite Gel Layers for Tissue Engineering Applications (Adv. Healthcare Mater. 5/2018)

In article number 1701385, Ponnambalam Ravi Selvaganapathy and co-workers use a lamination-based planar processing strategy enabled by nanoparticle adhesives to address one of the prominent technical challenges found in the tissue engineering field – the incorporation of perfusable hollow networks for nutrient and waste transport within artificial 3D tissue constructs. Without these vascular-like networks, the cells embedded within the constructs would quickly become necrotic. Silicon Carbide, used as a nanoadhesive, has been shown to be very effective in adhering microstructured layers of biologically important extracellular matrices containing collagen to form perfusable 3D netoworks suitable for growing cells.

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