Reply

Launay et al rightly point out that time to diagnosis research is vulnerable to several types of bias, and they reference a valuable reporting guideline (REST) intended to mitigate such bias. Our report was not free from potential bias, and we have specifically addressed the issue of selection bias in the paper's discussion. However, whereas adherence to the REST guideline is enviable—and would be valuable in any future effort to validate the findings of our study—this guideline should not necessarily be viewed as a methodologic minimum standard for the conduct or publication of time to diagnosis research.

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