Measurement of Tumor Hypoxia in Patients with Locally Advanced Cervical Cancer using Positron Emission Tomography (PET) with 18F-Fluoroazomyin Arabinoside (18F-FAZA)

Poor tumor oxygenation (hypoxia) is associated with inferior survival in cervical cancer and resistance to radiotherapy. Positron emission tomography (PET) imaging of tumor hypoxia is minimally invasive and allows evaluation of the entire tumor, but has not been widely studied in cervical cancer. This study assesses cervical tumor hypoxia using hypoxia tracer 18F-fluoroazomycin arabinoside (18F-FAZA), and compares different reference tissues and thresholds for quantifying tumor hypoxia.

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