Hard and soft tissue changes around implants activated using plasma of argon: A histomorphometric study in dog

Abstract

Objective

To histologically assess the hard and soft tissue changes after insertion of cleaned and activated titanium implants using plasma of argon.

Materials and methods

Eight dogs were included in this study. The mandibular premolars and first molars were extracted. For each hemi-mandible, four implants, 7 mm long and 3.3 mm of diameter, with a ZirTi surface were used. The surface of two implants was randomly treated with argon plasma (test), while the other two implants were left untreated (control). After 1 month, the same procedure was performed in the contralateral hemi-mandible. The amount of old bone, new bone, overall value of old bone plus new bone, and soft tissue was histologically evaluated.

Results

After 1 month of healing, high percentages of new bone in close contact with the implant surface were found at both the treated (60.1% ± 15.6%; 95% CI 56.5%–78.0%) and untreated (57.2% ± 13.1%; 95% CI 49.3%–67.5%) implants. Low percentages of old bone were found at this stage of healing, at both the treated (4.4% ± 3.0%; 95% CI 1.2%–5.4%) and untreated (3.4% ± 3.1%; 95% CI 0.6%–4.9%) implants. Not statistically significant differences were found between groups (p > .05). After 2 months of healing, treated implants presented a significantly higher (p = .012) new bone formation (72.5% ± 12.4%; 95% CI 69.6%–86.8%) compared to untreated sites (64.7% ± 17.3%; 95% CI 59.4%–83.3%). Controversially, no difference (p = .270) in terms of old bone was present between treated (3.1% ± 1.7%, 95% CI 1.8%–4.2%) and untreated implants (3.8% ± 1.9%, 95% CI 3.2%–5.8%). Significant differences (p = .018) in terms of total mineralized bone were found between treated (75.6% ± 13.0%, 95% CI 73.3%–91.3%) and untreated implants (68.4% ± 16.8%; 95% CI 64.2%–87.6%).

Conclusions

Implants treated using plasma of argon was demonstrated to reach a higher bone-to-implant contact when compared to untreated implants.

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