Antibody-Based Therapeutics: Ultrasensitive NIR-SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation (Adv. Healthcare Mater. 4/2018)

In article number 1700870, Yoon-Sik Lee and co-workers demonstrate in vivo validation process of candidate antibodies against human colon cancer, using a ratiometric quantification method. The validation is performed on a single mouse and analyzed by multiplexed surface-enhanced resonance Raman scattering (SERRS) with ultrasensitive and near-infrared (NIR)-active SERRS nanoprobes (NIR-SERRS dots).

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