Placenta-on-a-Chip: Placental Drug Transport-on-a-Chip: A Microengineered In Vitro Model of Transporter-Mediated Drug Efflux in the Human Placental Barrier (Adv. Healthcare Mater. 2/2018)

In article number 1700786, Dongeun Huh and co-workers present a micro-engineered model of the human placental barrier for investigation of maternal–fetal drug transfer in pregnancy. The placenta-on-a-chip system reconstitutes efflux transporter-mediated transport of a test compound, demonstrating proof-of-principle for use as a screening platform for prediction of drug transport in pregnancy.

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