Long Term Outcomes of Pediatric En Bloc Kidney Transplantation: A Single Center Experience with 25 Years Follow Up.

Background: Pediatric en bloc kidneys are considered marginal for transplantation into adults. We aimed to compare the long-term outcomes of pediatric en bloc vs. living donor kidney transplantation. Methods: A retrospective review was undertaken on pediatric en bloc and living donor kidney transplants performed at our center between 1990 and 2001. The outcomes compared between the groups included 25 year graft survival and longitudinal glomerular filtration rate (GFR). Results: There were 72 pediatric en bloc and 75 living donor kidney recipients included in the analysis. Pediatric donors were 16.9 +/- 11.2 months old and weighed 10.7+/-3.8 kg with terminal serum creatinine of 0.50+/-0.45 mg/dl. Living donors were 40.1+/-9.4 years old and serum creatinine was 0.90+/-0.16 mg/dl at the time of donation. En bloc kidney recipients had higher dialysis vintage (23.0 +/- 29.2 vs. 14.3 +/- 14.7 months, p=0.03), and longer cold ischemia time (30.5+/- 9.8 vs. 2.6 +/-0.9 hours, p

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