Protein adsorption on biomaterials' surfaces is a very complex process impacting biocompatibility and functionality of healthcare materials. The introduction of specific surface nanostructures is recognized as a powerful tool to control protein-surface interactions. In article number 1700995, Klaus D. Jandt and co-workers review nanostructured polymer surfaces represented by synthetic homopolymers, semicrystalline polymers and block copolymers, and their ability to control the amount, conformation, and selectivity of protein adsorption.
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