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Σάββατο 16 Δεκεμβρίου 2017

The selected biomarker analysis in five types of uterine smooth muscle tumors

Uterine smooth muscle tumors (USMT) consist of a group of histologically heterogeneous and clinically diverse diseases ranging from malignant leiomyosarcoma (LMS) to benign leiomyoma (ULM). The genetic alterations in LMS are complex with some genetic alterations present in both LMS and other atypical histologic variants of USMT. In this study we reviewed 119 USMT with a diagnosis of LMS, STUMP (smooth muscle tumor of uncertain malignant potential), ALM/LM-BN (atypical leiomyomas/leiomyoma with bizarre nuclei) and CLM (cellular leiomyoma) as well as 46 ULM and 60 myometrial controls.

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