Cryopreservation: Hydrogel Encapsulation Facilitates Rapid-Cooling Cryopreservation of Stem Cell-Laden Core–Shell Microcapsules as Cell–Biomaterial Constructs (Adv. Healthcare Mater. 23/2017)

Gang Zhao and co-workers develop a rapid cryopreservation method for large-volume stem cell hydrogel constructs in article number 1700988. Stem cells encapsulated in core-shell microcapsules retain their multipotential differentiation capability, and survive well when subjected to visible ice formation during cooling and subsequent ice formation during re-warming, a so-called devitrification process that is considered to be lethal for cells in long-term cryopreservation.

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