Tumor associated macrophages are strongly related to vascular invasion, non-luminal subtypes and interval breast cancer

Tumor associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion and show strong expression of CD163 in breast cancer. We here investigated the association between CD163 positive macrophages and vascular invasion, molecular subgroups, mode of detection, and patient outcome. We performed a population-based, retrospective study of invasive breast cancer from the Norwegian Breast Cancer Screening Programme in Vestfold County (2004–2009), including 200 screen-detected and 82 interval cancers.

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