Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells

Toda et al. demonstrate that the nucleoporin Nup153 interacts and cooperates with Sox2 to regulate the cellular state of neural progenitor cells. Nup153 binds both the 5′ and 3′ ends of genes, and the direction of gene regulation by Nup153 varies with the binding position of Nup153.

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