In Reply to Belderbos et al

To the Editor: We thank Belderbos et al for the astute comments regarding our recent article (1, 2). As we reiterated throughout the report, we concur that the results of our study should be considered hypothesis generating. We wholeheartedly agree that hippocampal avoidance should be used only in the context of clinical trials until we have more definitive data to support its safety and efficacy. In fact, the importance of the randomized studies and our desire to support these ongoing cooperative group efforts was our impetus to close our single-institution study and report the results for the patients enrolled to date.

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