Can We Define Bronchopulmonary Dysplasia?

The progression from severe respiratory distress syndrome (RDS) to lung injury was carefully described and named bronchopulmonary dysplasia (BPD) by Northway et al 50 years ago in a seminal report.1 The context for that report was very high mortality of moderately preterm infants from RDS because supplemental oxygen was the only effective therapy available in the late 1960s. Several neonatal services were trying to ventilate infants with RDS with minimal success until Gregory et al described the use of continuous positive airway pressure in 1971.

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