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Πέμπτη 8 Ιουνίου 2017

Cover Picture: Eur. J. Immunol. 6'17

Thumbnail image of graphical abstract

Our back cover shows a clonal colony-forming unit that emerges from dedicated cortical thymic epithelial cells of the murine thymus, as captured by high-content fluorescent microscope. The staining represents cytokeratin 8 (K8) (red), K5 (green) and DAPI (blue). The image was retrieved from Meireles et al. (pp. 958–969), who studied how the rules underlying the establishment of functionally competent cortical and medullary thymic epithelial cell (TEC) micro environments are regulated. Meireles and colleagues provide evidence that the postnatal cortex harbors cortical and medullary TEC progenitors and their abundance drops with age as result of continual thymic crosstalk.



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