Arterial Blood Pressure and Lifestyle Variability: In Quest of a Comprehensive Approach

The role of blood pressure variability (BPV) in the development of symptoms and target organs disease is a lasting object of investigations.^1,2 These were primarily triggered by the subjective reports of patients, a step usually not quoted specifically; subsequently, pioneering clinical observations³ were carried out, supported also by animal models research,⁴ but the effects of drugs on BPV⁵ and on clinical outcome and epidemiological studies⁶ are still the core of our present knowledge. BPV is approached as a clue distinct from and inclusive of the fluctuations related to the circadian rhythm, namely the day–night changes.⁷ However, the separate effects of physical exercise, sleep, digestive and other body functions, mood and emotional reactions are not fully detected, thus missing clues potentially useful for personalized intervention. Handy and friendly reference measurement, with an adequate timing of recording suitable for the purpose of guiding diagnosis for better targeting and monitoring interventions, is still a requirement that is not sufficiently satisfied.

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