Hematological and serum biochemical alterations in buffalo with some digestive disorders

Abstract

Hematological and serum biochemical reference intervals are essential laboratory variables for optimal diagnostic purposes. The present study was delineated to provide an insight into the hemato-biochemical alterations as well as the measurement of selected acute phase proteins in buffaloes showing some digestive disorders. The present study included 40 native breed water buffalo showing various symptoms of digestive troubles. Based on competent case history, clinical and laboratory findings, the diseased buffaloes were allocated into four equal sized groups, namely stomatitis, acute traumatic reticuloperitonitis (TRP), acute rumen impaction, and enteritis. Ten apparently healthy buffaloes were randomly selected from the same animal population and considered as control group. Blood samples were drawn from all investigated animals for hematologic examination and measurements of a panel of serum biochemical variables. All diseased buffaloes showed statistically significant high values of total leucocytes (P ≤ 0.05) with significantly low values of total erythrocytes and hemoglobin concentration compared with controls (P ≤ 0.05). Serum magnesium, sodium, and iron showed a statistically (P ≤ 0.05) lower values in all studied buffaloes than those of controls; while serum calcium levels were significantly decreased (P ≤ 0.05) in buffaloes showing stomatitis and those with TRP compared with controls. Serum hepatic enzyme activities beside serum haptoglobin and C-reactive protein were significantly (P ≤ 0.05) higher in all diseased buffaloes than those of controls. The results herein concluded that diseased buffalo were associated with marked hematological and elemental alterations besides a distinct inflammatory reaction. Further studies are needed to explore the potential ameliorative value of using supplementary agents to help mitigate the associated biochemical and inflammatory reactions in buffaloes exhibiting digestive disorders.

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